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Worrapong Kit-Anan

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Articles 13
Citations 175
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Recent Articles
1.
King O, Cruz-Moreira D, Sayed A, Kermani F, Kit-Anan W, Sunyovszki I, et al.
Cell Rep Methods . 2022 Sep; 2(9):100280. PMID: 36160044
In this study, we report static and perfused models of human myocardial-microvascular interaction. In static culture, we observe distinct regulation of electrophysiology of human induced pluripotent stem cell derived-cardiomyocytes (hiPSC-CMs)...
2.
Wang B, Kane C, Nicastro L, King O, Kit-Anan W, Downing B, et al.
Int J Mol Sci . 2022 Sep; 23(18). PMID: 36142853
Engagement of the sarcoplasmic reticulum (SR) Ca stores for excitation-contraction (EC)-coupling is a fundamental feature of cardiac muscle cells. Extracellular matrix (ECM) proteins that form the extracellular scaffolding supporting cardiac...
3.
Kim H, Yeow J, Najer A, Kit-Anan W, Wang R, Rifaie-Graham O, et al.
Adv Sci (Weinh) . 2022 Jul; 9(27):e2200239. PMID: 35901502
Constructing artificial systems that effectively replace or supplement natural biological machinery within cells is one of the fundamental challenges underpinning bioengineering. At the sub-cellular scale, artificial organelles (AOs) have significant...
4.
Wang B, Nicastro L, Couch L, Kit-Anan W, Downing B, MacLeod K, et al.
Cells . 2022 Apr; 11(7). PMID: 35406735
Cardiac fibroblasts regulate the development of the adult cardiomyocyte phenotype and cardiac remodeling in disease. We investigate the role that cardiac fibroblasts-secreted extracellular vesicles (EVs) have in the modulation of...
5.
Nunez-Toldra R, Kirwin T, Ferraro E, Pitoulis F, Nicastro L, Bardi I, et al.
ESC Heart Fail . 2022 Feb; 9(2):1400-1412. PMID: 35128823
Aims: Altered mechanical load in response to injury is a main driver of myocardial interstitial fibrosis. No current in vitro model can precisely modulate mechanical load in a multicellular environment...
6.
Jabbour R, Owen T, Pandey P, Reinsch M, Wang B, King O, et al.
JCI Insight . 2021 Aug; 6(15). PMID: 34369384
Engineered heart tissue (EHT) strategies, by combining cells within a hydrogel matrix, may be a novel therapy for heart failure. EHTs restore cardiac function in rodent injury models, but more...
7.
Pitoulis F, Nunez-Toldra R, Xiao K, Kit-Anan W, Mitzka S, Jabbour R, et al.
Cardiovasc Res . 2021 Mar; 118(3):814-827. PMID: 33723566
Aims: Cardiac remodelling is the process by which the heart adapts to its environment. Mechanical load is a major driver of remodelling. Cardiac tissue culture has been frequently employed for...
8.
Kit-Anan W, Mazo M, Wang B, Leonardo V, Pence I, Gopal S, et al.
Biofabrication . 2021 Mar; 13(2):025004. PMID: 33710972
Traditional in vitro bioengineering approaches whereby only individual biophysical cues are manipulated at any one time are highly inefficient, falling short when recapitulating the complexity of the cardiac environment. Multiple...
9.
Nele V, Schutt C, Wojciechowski J, Kit-Anan W, Doutch J, Armstrong J, et al.
Adv Mater . 2020 Jan; 32(7):e1905914. PMID: 31922627
Hydrogels are formed using various triggers, including light irradiation, pH adjustment, heating, cooling, or chemical addition. Here, a new method for forming hydrogels is introduced: ultrasound-triggered enzymatic gelation. Specifically, ultrasound...
10.
Wang Y, Kim E, Lin Y, Kim N, Kit-Anan W, Gopal S, et al.
ACS Appl Mater Interfaces . 2019 Jun; 11(26):22932-22940. PMID: 31252470
Programmable nucleic acids have emerged as powerful building blocks for the bottom-up fabrication of two- or three-dimensional nano- and microsized constructs. Here we describe the construction of organic-inorganic hybrid RNA...