Cesare M Terracciano
Overview
Explore the profile of Cesare M Terracciano including associated specialties, affiliations and a list of published articles.
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69
Citations
1473
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Recent Articles
1.
Vilaca A, Jesus C, Lino M, Hayman D, Emanueli C, Terracciano C, et al.
Mol Ther Nucleic Acids
. 2024 Jul;
35(3):102233.
PMID: 38974998
The delivery of therapeutic long non-coding RNAs (lncRNA) to the heart by extracellular vesicles (EVs) is promising for heart repair. H19, a lncRNA acting as a major regulator of gene...
2.
Pitoulis F, Smith J, Pamias-Lopez B, de Tombe P, Hayman D, Terracciano C
Exp Physiol
. 2023 Oct;
109(3):405-415.
PMID: 37847495
Mechanical load is one of the main determinants of cardiac structure and function. Mechanical load is studied in vitro using cardiac preparations together with loading protocols (e.g., auxotonic, isometric). However,...
3.
King O, Cruz-Moreira D, Sayed A, Kermani F, Kit-Anan W, Sunyovszki I, et al.
Cell Rep Methods
. 2022 Sep;
2(9):100280.
PMID: 36160044
In this study, we report static and perfused models of human myocardial-microvascular interaction. In static culture, we observe distinct regulation of electrophysiology of human induced pluripotent stem cell derived-cardiomyocytes (hiPSC-CMs)...
4.
Wang B, Kane C, Nicastro L, King O, Kit-Anan W, Downing B, et al.
Int J Mol Sci
. 2022 Sep;
23(18).
PMID: 36142853
Engagement of the sarcoplasmic reticulum (SR) Ca stores for excitation-contraction (EC)-coupling is a fundamental feature of cardiac muscle cells. Extracellular matrix (ECM) proteins that form the extracellular scaffolding supporting cardiac...
5.
Hachim D, Zhao J, Bhankharia J, Nunez-Toldra R, Brito L, Seong H, et al.
Small
. 2022 Jun;
18(36):e2202303.
PMID: 35770803
Non-viral vectors represent versatile and immunologically safer alternatives for nucleic acid delivery. Nanoneedles and high-aspect ratio nanostructures are unconventional but interesting delivery systems, in which delivery is mediated by surface...
6.
Wang B, Nicastro L, Couch L, Kit-Anan W, Downing B, MacLeod K, et al.
Cells
. 2022 Apr;
11(7).
PMID: 35406735
Cardiac fibroblasts regulate the development of the adult cardiomyocyte phenotype and cardiac remodeling in disease. We investigate the role that cardiac fibroblasts-secreted extracellular vesicles (EVs) have in the modulation of...
7.
Nunez-Toldra R, Kirwin T, Ferraro E, Pitoulis F, Nicastro L, Bardi I, et al.
ESC Heart Fail
. 2022 Feb;
9(2):1400-1412.
PMID: 35128823
Aims: Altered mechanical load in response to injury is a main driver of myocardial interstitial fibrosis. No current in vitro model can precisely modulate mechanical load in a multicellular environment...
8.
van der Velden J, Asselbergs F, Bakkers J, Batkai S, Bertrand L, Bezzina C, et al.
Cardiovasc Res
. 2022 Jan;
118(15):3016-3051.
PMID: 34999816
Cardiovascular diseases represent a major cause of morbidity and mortality, necessitating research to improve diagnostics, and to discover and test novel preventive and curative therapies, all of which warrant experimental...
9.
Jabbour R, Owen T, Pandey P, Reinsch M, Wang B, King O, et al.
JCI Insight
. 2021 Aug;
6(15).
PMID: 34369384
Engineered heart tissue (EHT) strategies, by combining cells within a hydrogel matrix, may be a novel therapy for heart failure. EHTs restore cardiac function in rodent injury models, but more...
10.
Couch L, Fiedler J, Chick G, Clayton R, Dries E, Wienecke L, et al.
Cardiovasc Res
. 2021 Jun;
118(7):1758-1770.
PMID: 34155498
Aims: Takotsubo syndrome (TTS) is an acute heart failure, typically triggered by high adrenaline during physical or emotional stress. It is distinguished from myocardial infarction (MI) by a characteristic pattern...