Isaac J Pence
Overview
Explore the profile of Isaac J Pence including associated specialties, affiliations and a list of published articles.
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Articles
35
Citations
452
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Recent Articles
1.
Iliopoulos F, Tu D, Pence I, Li X, Ghosh P, Luke M, et al.
J Control Release
. 2024 Feb;
367:864-876.
PMID: 38346503
Generic drugs are essential for affordable medicine and improving accessibility to treatments. Bioequivalence (BE) is typically demonstrated by assessing a generic product's pharmacokinetics (PK) relative to a reference-listed drug (RLD)....
2.
Buchanan L, Domingo M, White S, Vanoven T, Karbasion N, Bersi M, et al.
Curr Res Physiol
. 2023 Dec;
6:100111.
PMID: 38107786
No abstract available.
3.
Wei Y, Pence I, Wiatrowski A, Slade J, Evans C
Analyst
. 2023 Dec;
149(5):1436-1446.
PMID: 38050860
Pharmaceutical development of solid-state formulations requires testing active pharmaceutical ingredients (API) and excipients for uniformity and stability. Solid-state properties such as component distribution and grain size are crucial factors that...
4.
Moradi Tuchayi S, Wang Y, Khodorova A, Pence I, Stemmer-Rachamimov A, Evans C, et al.
Sci Rep
. 2022 Nov;
12(1):19891.
PMID: 36400878
Cryoneurolysis is an opioid-sparing therapy for long-lasting and reversible reduction of pain. We developed a nerve-selective method for cryoneurolysis by local injection of ice-slurry (- 5 to - 6 °C)...
5.
Moradi Tuchayi S, Wang Y, Pence I, Fast A, Stemmer-Rachamimov A, Evans C, et al.
J Pain Res
. 2022 Sep;
15:2905-2910.
PMID: 36132994
Background: Cryoneurolysis uses tissue cooling as an opioid-sparing, long-lasting treatment for peripheral nerve pain. A nerve-selective method for cryoneurolysis by local injection of ice-slurry was developed to allow cryoneurolysis to...
6.
Moradi Tuchayi S, Wang Y, Khodorova A, Pence I, Evans C, Anderson R, et al.
J Invest Dermatol
. 2022 Aug;
143(1):134-141.e1.
PMID: 35985498
Cutaneous pain is a common symptom of skin disease, and available therapies are inadequate. We developed a neural selective and injectable method of cryoneurolysis with ice slurry, which leads to...
7.
Barriga H, Pence I, Holme M, Doutch J, Penders J, Nele V, et al.
Adv Mater
. 2022 Mar;
34(26):e2200839.
PMID: 35358374
Lipid nanoparticles (LNPs) are versatile structures with tunable physicochemical properties that are ideally suited as a platform for vaccine delivery and RNA therapeutics. A key barrier to LNP rational design...
8.
Kuzma B, Pence I, Ho A, Evans C
J Vis Exp
. 2021 Dec;
(177).
PMID: 34897272
Cutaneous pharmacokinetics (cPK) after topical formulation application has been a research area of particular interest for regulatory and drug development scientists to mechanistically understand topical bioavailability (BA). Semi-invasive techniques, such...
9.
Pence I, Kuzma B, Brinkmann M, Hellwig T, Evans C
Biomed Opt Express
. 2021 Nov;
12(10):6095-6114.
PMID: 34745724
Stimulated Raman scattering (SRS) is a nondestructive and rapid technique for imaging of biological and clinical specimens with label-free chemical specificity. SRS spectral imaging is typically carried out either via...
10.
Penders J, Nagelkerke A, Cunnane E, Pedersen S, Pence I, Coombes R, et al.
ACS Nano
. 2021 Nov;
15(11):18192-18205.
PMID: 34735133
Extracellular vesicles (EVs) secreted by cancer cells provide an important insight into cancer biology and could be leveraged to enhance diagnostics and disease monitoring. This paper details a high-throughput label-free...