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Woon-Puay Koh

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Articles 424
Citations 11643
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Recent Articles
1.
Jain P, Ng H, Tay D, Mina T, Low D, Sadhu N, et al.
medRxiv . 2025 Feb; PMID: 39990582
To identify biomarkers and pathways to Type-2 diabetes (T2D), a major global disease, we completed array-based epigenome-wide association in whole blood in 5,709 Asian people. We found 323 Sentinel CpGs...
2.
Chang X, Shih C, Chen J, Lee A, Tan P, Wang L, et al.
medRxiv . 2025 Feb; PMID: 39990559
Background: Existing polygenic scores (PGS) are derived primarily from studies performed in European populations. It is still unclear how these perform in improving risk predictions in East-Asians. Methods: We generated...
3.
Kanis J, Johansson H, McCloskey E, Liu E, Schini M, Vandenput L, et al.
Osteoporos Int . 2025 Feb; PMID: 39955689
Introduction: RA is a well-documented risk factor for subsequent fracture that is incorporated into the FRAX algorithm. The aim of this study was to evaluate, in an international meta-analysis, the...
4.
Tay J, Wang W, Guan L, Dorajoo R, Khor C, Feng L, et al.
J Gerontol A Biol Sci Med Sci . 2025 Jan; PMID: 39869450
Deoxyribonucleic acid (DNA) methylation (DNAm) clocks estimate biological age according to DNA methylation. This study investigated the associations between measures of physical function and physical performance and ten DNAm clocks...
5.
Ying A, Hausenloy D, Koh W
Environ Health Perspect . 2025 Jan; 133(1):17009. PMID: 39853267
Background: Epidemiologic studies have shown that daily exposure to incense smoke is associated with greater risk of cardiovascular mortality, which suggests that chronic exposure to incense could be linked to...
6.
Chua K, Tan K, Tong R, Barrenetxea J, Koh W, Chen C
BMC Public Health . 2025 Jan; 25(1):290. PMID: 39849425
Background: Weak handgrip strength and slow timed up-and-go (TUG) time are known risk factors for hospitalization among older adults; however, few studies have investigated the relationships between these physical tests...
7.
Merritt M, Abe S, Islam M, Rahman M, Saito E, Katagiri R, et al.
Br J Cancer . 2024 Dec; 132(4):361-370. PMID: 39706987
Background: There are scarce data on risk factors for epithelial ovarian cancer (EOC) in Asian populations. Our goal was to advance knowledge on reproductive -related risk factors for EOC in...
8.
Chng A, Tan H, Teo L, Tan R, Ewe S, Leng S, et al.
Geroscience . 2024 Oct; PMID: 39397221
Background: Glycated haemoglobin (HbA1c) is a well-established biomarker for diabetes diagnosis and management and is linked to risk of cardiovascular death. However, among adults without cardiovascular disease (CVD) and diabetes,...
9.
Li H, Tai B, Pan A, Koh W
BJPsych Open . 2024 Oct; 10(6):e179. PMID: 39391913
Background: The prospective association between sleep duration and the development of late-life depressive symptomology is unclear. Aims: To investigate sleep duration from midlife to late life in relation to risk...
10.
Abe S, Nishio M, Huang H, Leung C, Islam M, Rahman M, et al.
Public Health . 2024 Oct; 237:130-134. PMID: 39368404
Objectives: To evaluate changes in the age at menarche in Asian populations. Study Design: Retrospective cohort study. Methods: We included 548,830 women from six countries in Asia. The data were...