Won-Mo Yang
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Explore the profile of Won-Mo Yang including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
361
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Recent Articles
1.
Pittala S, Haspula D, Cui Y, Yang W, Kim Y, Davis R, et al.
Nat Commun
. 2024 Nov;
15(1):9996.
PMID: 39557854
Altered hepatic glucose fluxes are critical during the pathogenesis of type 2 diabetes. G protein-coupled receptors represent important regulators of hepatic glucose production. Recent studies have shown that hepatocytes express...
2.
da Cruz Rodrigues K, Kim S, Uner A, Hou Z, Young J, Campolim C, et al.
Mol Metab
. 2024 Apr;
84:101941.
PMID: 38636794
Objective: Low-density lipoprotein receptor-related protein-1 (LRP1) regulates energy homeostasis, blood-brain barrier integrity, and metabolic signaling in the brain. Deficiency of LRP1 in inhibitory gamma-aminobutyric acid (GABA)ergic neurons causes severe obesity...
3.
LRP1 mediates leptin transport by coupling with the short-form leptin receptor in the choroid plexus
Uner A, Yang W, Kang M, da Cruz Rodrigues K, Aydogan A, Seo J, et al.
bioRxiv
. 2023 Jul;
PMID: 37461530
Adipocyte-derived leptin enters the brain to exert its anorexigenic action, yet its transport mechanism is poorly understood. Here we report that LRP1 (low-density lipoprotein receptor-related protein-1) mediates the transport of...
4.
Sung B, Lim S, Yang W, Kim J, Kulkarni R, Kim Y, et al.
Mol Metab
. 2022 Nov;
66:101625.
PMID: 36374631
Objective: The endocrine pancreatic β-cells play a pivotal role in maintaining whole-body glucose homeostasis and its dysregulation is a consistent feature in all forms of diabetes. However, knowledge of intracellular...
5.
Kang M, Seo J, Lee H, Uner A, Yang W, da Cruz Rodrigues K, et al.
Am J Physiol Endocrinol Metab
. 2020 Dec;
320(2):E379-E389.
PMID: 33356995
Low-density lipoprotein receptor-related protein 1 (LRP1) is a member of LDL receptor family that plays a key role in systemic glucose and lipid homeostasis. LRP1 also regulates energy balance in...
6.
Seo J, Kang M, Yang W, Hwang W, Kim S, Hong S, et al.
Nat Commun
. 2020 May;
11(1):2276.
PMID: 32371884
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
7.
Seo J, Kang M, Yang W, Hwang W, Kim S, Hong S, et al.
Nat Commun
. 2020 Apr;
11(1):2024.
PMID: 32332780
Crosstalk between liver and skeletal muscle is vital for glucose homeostasis. Hepatokines, liver-derived proteins that play an important role in regulating muscle metabolism, are important to this communication. Here we...
8.
Huang H, Lee S, Sousa-Lima I, Kim S, Hwang W, Dagon Y, et al.
J Clin Invest
. 2018 Sep;
128(12):5335-5350.
PMID: 30226474
Obesity is a major risk factor for developing nonalcoholic fatty liver disease (NAFLD). NAFLD is the most common form of chronic liver disease and is closely associated with insulin resistance,...
9.
Min K, Yang W, Lee W
Biochem Biophys Res Commun
. 2018 Jul;
503(3):1587-1593.
PMID: 30033101
The excessive intake of saturated fatty acids (SFA) causes obesity and liver steatosis, which are major risk factors for insulin resistance and type 2 diabetes. Although the expression of certain...
10.
Yang W, Min K, Park S, Lee W
Data Brief
. 2017 Nov;
15:882-886.
PMID: 29159225
The ectopic expression of miR-15b is linked causally to impaired insulin signaling in human HepG2 hepatocytes through the suppression of INSR (Yang et al., 2015) [1]. In this data article,...