Wolfram Saenger
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Explore the profile of Wolfram Saenger including associated specialties, affiliations and a list of published articles.
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100
Citations
3021
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Recent Articles
1.
Banchenko S, Weise C, Lanka E, Saenger W, Geibel S
ACS Omega
. 2021 Nov;
6(43):28903-28911.
PMID: 34746582
During DNA replication, primases synthesize oligonucleotide primers on single-stranded template DNA, which are then extended by DNA polymerases to synthesize a complementary DNA strand. Primase RepB' of plasmid RSF1010 initiates...
2.
Steiner T, Saenger W
Angew Chem Int Ed Engl
. 2018 May;
37(24):3404-3407.
PMID: 29711281
Glucose-flips in a small cycloamylose: the molecular structure of permethylated γ-cyclodextrin, which crystallizes as the dihydrate, is characterized by 180° flips of two diametrically opposed glucose residues. This leads to...
3.
Jacob J, Gessler K, Hoffmann D, Sanbe H, Koizumi K, Smith S, et al.
Angew Chem Int Ed Engl
. 2018 May;
37(5):605-609.
PMID: 29711068
The cavity of the larger molecule has less space for guests! Unlike the structure of the smaller annular cyclodextrins, that of the higher homologues of cycloamyloses (CAs) with more than...
4.
Wedepohl S, Dernedde J, Vahedi-Faridi A, Tauber R, Saenger W, Bulut H
Chembiochem
. 2017 May;
18(13):1338-1345.
PMID: 28489325
L-Selectin, a cell-adhesion receptor on the surface of most leukocytes, contains seven N-glycosylation sites. In order to obtain the crystal structure of human L-selectin, we expressed a shortened version of...
5.
Roth C, Weizenmann N, Bexten N, Saenger W, Zimmermann W, Maier T, et al.
Sci Adv
. 2017 Jan;
3(1):e1601386.
PMID: 28097217
Starch is a major carbon and energy source throughout all kingdoms of life. It consists of two carbohydrate polymers, branched amylopectin and linear amylose, which are sparingly soluble in water....
6.
Martinez J, Nguyen L, Hinderlich S, Zimmer R, Tauberger E, Reutter W, et al.
J Biol Chem
. 2012 Feb;
287(17):13656-65.
PMID: 22343627
Sialic acids are essential components of membrane glycoconjugates. They are responsible for the interaction, structure, and functionality of all deuterostome cells and have major functions in cellular processes in health...
7.
Bulut H, Ma Q, Moniot S, Saenger W, Schneider E, Vahedi-Faridi A
Eur J Cell Biol
. 2012 Feb;
91(4):318-25.
PMID: 22341528
This paper briefly reviews contemporary protein crystallography and focuses on six receptor proteins of membrane-intrinsic ATP binding cassette (ABC) transporters. Three of these receptors are specific for carbohydrates and three...
8.
Bulut H, Moniot S, Licht A, Scheffel F, Gathmann S, Saenger W, et al.
J Mol Biol
. 2011 Dec;
415(3):560-72.
PMID: 22138345
ATP-binding cassette (ABC) transporters are integral membrane proteins that carry a variety of substrates across biological membranes at the expense of ATP. The here considered prokaryotic canonical importers consist of...
9.
10.
Fan H, Tansi F, Weihofen W, Bottcher C, Hu J, Martinez J, et al.
Eur J Cell Biol
. 2011 Aug;
91(4):265-73.
PMID: 21856036
Dipeptidyl peptidase IV (DPPIV or CD26) is a multifunctional membrane glycoprotein. As an exopeptidase it regulates the activity of a series of biologically important peptides. Through its interaction with specific...