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Ardeschir Vahedi-Faridi

Explore the profile of Ardeschir Vahedi-Faridi including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 415
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Recent Articles
1.
Michenkova M, Taki S, Blosser M, Hwang H, Kowatz T, Moss F, et al.
Interface Focus . 2021 Feb; 11(2):20200090. PMID: 33633837
Carbon dioxide (CO) movement across cellular membranes is passive and governed by Fick's law of diffusion. Until recently, we believed that gases cross biological membranes exclusively by dissolving in and...
2.
Moss F, Mahinthichaichan P, Lodowski D, Kowatz T, Tajkhorshid E, Engel A, et al.
Front Physiol . 2020 Jul; 11:728. PMID: 32695023
oocytes expressing human aquaporin-7 (AQP7) exhibit greater osmotic water permeability and H-glycerol uptake vs. those expressing the bacterial glycerol facilitator GlpF. AQP7-expressing oocytes exposed to increasing extracellular [glycerol] under isosmolal...
3.
Wedepohl S, Dernedde J, Vahedi-Faridi A, Tauber R, Saenger W, Bulut H
Chembiochem . 2017 May; 18(13):1338-1345. PMID: 28489325
L-Selectin, a cell-adhesion receptor on the surface of most leukocytes, contains seven N-glycosylation sites. In order to obtain the crystal structure of human L-selectin, we expressed a shortened version of...
4.
Blankenship E, Vahedi-Faridi A, Lodowski D
Structure . 2015 Nov; 23(12):2358-2364. PMID: 26526852
Rhodopsin, a light-activated G protein coupled receptor (GPCR), has been the subject of numerous biochemical and structural investigations, serving as a model receptor for GPCRs and their activation. We present...
5.
Ding F, Lee K, Vahedi-Faridi A, Yoneyama H, Osgood C, Xu X
Analyst . 2014 May; 139(12):3088-96. PMID: 24781334
Multidrug membrane transporters (efflux pumps) can selectively extrude a variety of structurally and functionally diverse substrates (e.g., chemotoxics, antibiotics), leading to multidrug resistance (MDR) and ineffective treatment of a wide...
6.
Vahedi-Faridi A, Jastrzebska B, Palczewski K, Engel A
Microscopy (Oxf) . 2012 Dec; 62(1):95-107. PMID: 23267047
Inherently unstable, detergent-solubilized membrane protein complexes can often not be crystallized. For complexes that have a mass of >300 kDa, cryo-electron microscopy (EM) allows their three-dimensional (3D) structure to be...
7.
Bulut H, Ma Q, Moniot S, Saenger W, Schneider E, Vahedi-Faridi A
Eur J Cell Biol . 2012 Feb; 91(4):318-25. PMID: 22341528
This paper briefly reviews contemporary protein crystallography and focuses on six receptor proteins of membrane-intrinsic ATP binding cassette (ABC) transporters. Three of these receptors are specific for carbohydrates and three...
8.
Ding F, Lee K, Vahedi-Faridi A, Huang T, Xu X
Anal Bioanal Chem . 2011 Feb; 400(1):223-35. PMID: 21336797
We have designed and constructed fusion genes of C-terminal (Ct) or N-terminal (Nt) bmrA with EGFP vectors and successfully expressed them in ΔBmrA (BmrA deletion strain of Bacillus subtilis), generating...
9.
Licht A, Bulut H, Scheffel F, Daumke O, Wehmeier U, Saenger W, et al.
J Mol Biol . 2010 Dec; 406(1):92-105. PMID: 21168419
Solute receptors (binding proteins) are indispensable components of canonical ATP-binding cassette importers in prokaryotes. Here, we report on the characterization and crystal structures in the closed and open conformations of...
10.
Porta J, Vahedi-Faridi A, Borgstahl G
J Mol Biol . 2010 Apr; 399(3):377-84. PMID: 20417642
The superoxide dismutase (SOD) enzymes are important antioxidant agents that protect cells from reactive oxygen species. The SOD family is responsible for catalyzing the disproportionation of superoxide radical to oxygen...