Wojciech Plazinski
Overview
Explore the profile of Wojciech Plazinski including associated specialties, affiliations and a list of published articles.
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93
Citations
447
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Recent Articles
1.
Lutsyk V, Plazinski W
J Phys Chem B
. 2025 Feb;
129(9):2408-2425.
PMID: 39988846
Hyaluronan, also known as hyaluronic acid, is a large glycosaminoglycan composed of repeating disaccharide units. It plays a crucial role in providing structural support, hydration, and facilitating cellular processes in...
2.
Kolodziej-Sobczak D, Sobczak L, Plazinski W, Slawinska-Brych A, Mizerska-Kowalska M, Holub K, et al.
Sci Rep
. 2025 Feb;
15(1):4892.
PMID: 39929933
This work presents a rational synthesis of 14 innovative methyl salicylate based thiazole (MSBT) derivatives, designed as protein tyrosine phosphatase 1B (PTP1B) inhibitors with potent anticancer activity. Enzyme inhibition studies...
3.
Michna A, Lupa D, Plazinski W, Batys P, Adamczyk Z
Adv Colloid Interface Sci
. 2024 Dec;
337():103383.
PMID: 39733532
Chitosan, a biocompatible polysaccharide, finds a wide range of applications, inter alia as an antimicrobial agent, stabilizer of food products, cosmetics, and in the targeted delivery of drugs and stem...
4.
Plazinski W, Archala A, Jozwiak K, Plazinska A
Proteins
. 2024 Nov;
93(3):728-744.
PMID: 39548888
Biased agonism in G protein-coupled receptors is a phenomenon resulting in the selective activation of distinct intracellular signaling pathways by different agonists, which may exhibit bias toward either Gs, Gi,...
5.
Brzyska A, Plazinski W
Carbohydr Res
. 2024 Oct;
545:109294.
PMID: 39471537
In this study, the mechanism and nature of mechanical force-induced conformational transitions of alginate oligomers with different ratios of β-d-mannuronic acid (M unit) and α-l-guluronic acid (G unit) units were...
6.
Donarska B, Cytarska J, Kolodziej-Sobczak D, Studzinska R, Kupczyk D, Baranowska-Laczkowska A, et al.
Molecules
. 2024 Oct;
29(19).
PMID: 39407644
The presented study depicts the synthesis of 11 carborane-thiazole conjugates with anticancer activity, as well as an evaluation of their biological activity as inhibitors of two enzymes: tyrosinase and 11β-hydroxysteroid...
7.
Lutsyk V, Wolski P, Plazinski W
J Chem Theory Comput
. 2024 Jul;
20(14):6350-6368.
PMID: 38985993
The conformational features of the glycosidic linkage are the most important variable to consider when studying di-, oligo-, and polysaccharide molecules using molecular dynamics (MD) simulations. The accuracy of the...
8.
Flieger J, Zuk N, Pasieczna-Patkowska S, Kusmierz M, Panek R, Franus W, et al.
Int J Mol Sci
. 2024 Mar;
25(6).
PMID: 38542125
In recent years, there has been a growing interest in plant pigments as readily available nutraceuticals. Photosynthetic pigments, specifically chlorophylls and carotenoids, renowned for their non-toxic antioxidant properties, are increasingly...
9.
Plazinski W, Lutsyk V, Plazinska A
J Chem Theory Comput
. 2024 Mar;
20(5):2273-2283.
PMID: 38427574
Coarse-grained (CG) level molecular dynamics simulations are routinely used to study various biomolecular processes. The Martini force field is currently the most widely adopted parameter set for such simulations. The...
10.
Lutsyk V, Plazinski W
J Phys Chem B
. 2024 Jan;
128(2):472-491.
PMID: 38170925
The study focuses on the conformational properties of biologically relevant monosaccharides belonging to the group of uronates: α-l-iduronate, O-sulfated-α-l-iduronate, and O-sulfated-α-l-guluronate, either unfunctionalized or O-methylated. We applied the previously proposed...