Wojciech Plazinski
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Explore the profile of Wojciech Plazinski including associated specialties, affiliations and a list of published articles.
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93
Citations
447
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Recent Articles
11.
Stepnik K, Kukula-Koch W, Plazinski W, Rybicka M, Gawel K
Pharmaceuticals (Basel)
. 2023 Sep;
16(9).
PMID: 37765042
Oleanolic acid (OA), as a ubiquitous compound in the plant kingdom, is studied for both its neuroprotective and neurotoxic properties. The mechanism of acetylcholinesterase (AChE) inhibitory potential of OA is...
12.
Stepnik K, Kukula-Koch W, Plazinski W
Biomolecules
. 2023 Sep;
13(9).
PMID: 37759757
The acetylcholinesterase-inhibitory potential of the oleanane-type triterpenes and their glycosides from thebark of (Combreatceae), i.e.,arjunic acid, arjunolic acid, arjungenin, arjunglucoside I, sericic acid and arjunetin, is presented. The studies are...
13.
Plazinski W, Angles dOrtoli T, Widmalm G
Org Biomol Chem
. 2023 Aug;
21(34):6979-6994.
PMID: 37584331
Carbohydrates in biological systems are referred to as glycans and modification of their structures is a hallmark indicator of disease. Analysis of the three-dimensional structure forms the basis for further...
14.
Stepnik K, Kukula-Koch W, Plazinski W, Gawel K, Gawel-Beben K, Khurelbat D, et al.
Int J Mol Sci
. 2023 Jun;
24(11).
PMID: 37298103
The main aim of the study was to assess the acetylcholinesterase-inhibitory potential of triterpenoid saponins (astragalosides) found in the roots of . For this purpose, the TLC bioautography method was...
15.
Donarska B, Slawinska-Brych A, Mizerska-Kowalska M, Zdzisinska B, Plazinski W, Laczkowski K
Bioorg Chem
. 2023 May;
138:106608.
PMID: 37207596
Here, we rationally designed a human neutrophil elastase (HNE) inhibitors 4a-4f derived from thalidomide. The HNE inhibition assay showed that synthesized compounds 4a, 4b, 4e and 4f demonstrated strong HNE...
16.
Baumgart S, Kupczyk D, Archala A, Koszla O, Solek P, Plazinski W, et al.
Int J Mol Sci
. 2023 Apr;
24(8).
PMID: 37108415
In this study, a series of nine new 2-(cyclopentylamino)thiazol-4(5)-one derivatives were synthesized, and their anticancer, antioxidant, and 11β-hydroxysteroid dehydrogenase (11β-HSD) inhibitory activities were tested. Anticancer activity has been assessed using...
17.
Kwiatkowski P, Tabis A, Sobolewski P, Plazinski W, Pruss A, Sienkiewicz M, et al.
PLoS One
. 2023 Apr;
18(4):e0284042.
PMID: 37027379
This study aimed to analyze the chemotactic response of differentiated HL-60 neutrophil-like (dHL-60) cells to trans-anethole (TA)-treated Staphylococcus aureus strains. Special attention was paid to evaluate the influence of TA...
18.
Maciag M, Plazinski W, Pulawski W, Kolinski M, Jozwiak K, Plazinska A
Biomed Pharmacother
. 2023 Feb;
160:114355.
PMID: 36739761
β-adrenergic receptors (βARs) belong to a key molecular targets that regulate the most important processes occurring in the human organism. Although over the last decades a zebrafish model has been...
19.
Panczyk T, Plazinski W, Dupradeau F, Brzyska A, Wolski P
Molecules
. 2023 Jan;
28(2).
PMID: 36677880
Interaction of β-D-glucopyranuronic acid (GlcA), N-acetyl-β-D-glucosamine (GlcNAc), N-acetyl-β-D-galactosamine (GalNAc) and two natural decameric glycosaminoglycans, hyaluronic acid (HA) and Chondroitin (Ch) with carboxylated carbon nanotubes, were studied using molecular dynamics simulations...
20.
Donarska B, Switalska M, Wietrzyk J, Plazinski W, Laczkowski K
Int J Mol Sci
. 2023 Jan;
24(1).
PMID: 36613577
Herein, nine phthalimide-based thiazoles (-) were synthesized and investigated as new human neutrophil elastase (HNE) inhibitors using spectrofluorimetric and computational methods. The most active compounds containing 4-trifluoromethyl (), 4-naphthyl ()...