Wim E Hennink
Overview
Explore the profile of Wim E Hennink including associated specialties, affiliations and a list of published articles.
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428
Citations
9245
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Recent Articles
11.
Ilochonwu B, van der Lugt S, Annala A, di Marco G, Sampon T, Siepmann J, et al.
J Control Release
. 2023 Aug;
361:334-349.
PMID: 37532147
In the present study, a novel in situ forming thermosensitive hydrogel system was investigated as a versatile drug delivery system for ocular therapy. For this purpose, two thermosensitive ABA triblock...
12.
Liu M, Lau C, Cabello I, Garssen J, Willemsen L, Hennink W, et al.
Pharmaceuticals (Basel)
. 2023 Jun;
16(6).
PMID: 37375766
Our previous study demonstrated that a selected β-lactoglobulin-derived peptide (BLG-Pep) loaded in poly(lactic--glycolic acid) (PLGA) nanoparticles protected mice against cow's milk allergy development. However, the mechanism(s) responsible for the interaction...
13.
Casadidio C, Mayol L, Biondi M, Scuri S, Cortese M, Hennink W, et al.
Int J Pharm
. 2023 Mar;
636:122798.
PMID: 36889417
Chemical and enzymatic in vivo degradation of antimicrobial peptides represents a major challenge for their therapeutic use to treat bacterial infections. In this work, anionic polysaccharides were investigated for their...
14.
Priwitaningrum D, Pednekar K, Gabriel A, Varela-Moreira A, Le Gac S, Vellekoop I, et al.
Drug Deliv Transl Res
. 2023 Feb;
13(5):1470-1483.
PMID: 36853438
Since tumor stroma poses as a barrier to achieve efficacy of nanomedicines, it is essential to evaluate nano-chemotherapeutics in stroma-mimicking 3D models that reliably predict their behavior regarding these hurdles...
15.
Annala A, Ilochonwu B, Wilbie D, Sadeghi A, Hennink W, Vermonden T
ACS Polym Au
. 2023 Feb;
3(1):118-131.
PMID: 36785837
The aim of this study was to develop an injectable hydrogel delivery system for sustained ocular delivery of dexamethasone. To this end, a self-healing hydrogel consisting of a thermosensitive ABA...
16.
Liu M, Thijssen S, Hennink W, Garssen J, van Nostrum C, Willemsen L
Front Immunol
. 2023 Jan;
13:1053107.
PMID: 36703973
Cow's milk allergy is a common food allergy among infants. Improved hygiene conditions and loss of microbial diversity are associated with increased risk of allergy development. The intestinal immune system...
17.
Lau C, Fontana F, Mandemaker L, Wezendonk D, Vermeer B, Bonvin A, et al.
Commun Chem
. 2023 Jan;
3(1):179.
PMID: 36703417
No abstract available.
18.
Lau C, Fontana F, Mandemaker L, Wezendonk D, Vermeer B, Bonvin A, et al.
Commun Chem
. 2023 Jan;
3(1):164.
PMID: 36703336
Self-assembling peptides are an exemplary class of supramolecular biomaterials of broad biomedical utility. Mechanistic studies on the peptide self-assembly demonstrated the importance of the oligomeric intermediates towards the properties of...
19.
Yanev P, van Tilborg G, Boere K, Stowe A, van der Toorn A, Viergever M, et al.
ACS Biomater Sci Eng
. 2023 Jan;
9(2):760-772.
PMID: 36681938
Hydrogels have been suggested as novel drug delivery systems for sustained release of therapeutic proteins in various neurological disorders. The main advantage these systems offer is the controlled, prolonged exposure...
20.
Mesquita B, Fens M, Di Maggio A, Bosman E, Hennink W, Heger M, et al.
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499301
Nanoparticles (NPs) are commonly modified with tumor-targeting moieties that recognize proteins overexpressed on the extracellular membrane to increase their specific interaction with target cells. Nanobodies (Nbs), the variable domain of...