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Willy Put

Explore the profile of Willy Put including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 11
Citations 352
Followers 0
Related Specialties
Allergy & Immunology
Pathology
Hematology
Top 10 Co-Authors
Jo Van Damme
Sofie Struyf
Paul Proost
Mieke Gouwy
Ghislain Opdenakker
Evemie Schutyser
Isabelle Ronsse
Bernard Grillet
Jean-Pierre Lenaerts
Rene Conings
Published In
J Leukoc Biol
Lab Invest
Blood
Mol Pharmacol
Eur J Immunol
Affiliations
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Recent Articles
1.
Carcinoma cell-derived chemokines and their presence in oral fluid
Michiels K, Schutyser E, Conings R, Lenaerts J, Put W, Nuyts S, et al.
Eur J Oral Sci . 2009 Jul; 117(4):362-8. PMID: 19627345
Chemokines are important in inflammation and in carcinogenesis. We hypothesized that besides oro-laryngeal cancer, oral inflammatory states, such as periodontitis, may also influence the chemokine profile of oral fluid. The...
2.
CC chemokine ligand-2 synergizes with the nonchemokine G protein-coupled receptor ligand fMLP in monocyte chemotaxis, and it cooperates with the TLR ligand LPS via induction of CXCL8
Gouwy M, Struyf S, Verbeke H, Put W, Proost P, Opdenakker G, et al.
J Leukoc Biol . 2009 May; 86(3):671-80. PMID: 19451399
During inflammatory reactions, endogenously produced cytokines and chemokines act in a network and interact with hormones and neurotransmitters to regulate host immune responses. These signaling circuitries are even more interfaced...
3.
Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation
Loos T, Mortier A, Gouwy M, Ronsse I, Put W, Lenaerts J, et al.
Blood . 2008 Jul; 112(7):2648-56. PMID: 18645041
Interactions between chemokines and enzymes are vital in immunoregulation. Structural protein citrullination by peptidylarginine deiminase (PAD) has been associated with autoimmunity. In this report, we identified a novel naturally occurring...
4.
Stimulation of angiostatic platelet factor-4 variant (CXCL4L1/PF-4var) versus inhibition of angiogenic granulocyte chemotactic protein-2 (CXCL6/GCP-2) in normal and tumoral mesenchymal cells
Vandercappellen J, Noppen S, Verbeke H, Put W, Conings R, Gouwy M, et al.
J Leukoc Biol . 2007 Sep; 82(6):1519-30. PMID: 17827342
Chemokines affect inflammation and cancer through leukocyte attraction and angiogenesis. Here, we demonstrate that CXCL4L1/platelet factor-4 variant (PF-4var), a highly angiostatic chemokine, is poorly chemotactic for phagocytes and is inducible...
5.
Proteolytic processing of CXCL11 by CD13/aminopeptidase N impairs CXCR3 and CXCR7 binding and signaling and reduces lymphocyte and endothelial cell migration
Proost P, Mortier A, Loos T, Vandercappellen J, Gouwy M, Ronsse I, et al.
Blood . 2007 Mar; 110(1):37-44. PMID: 17363734
CXCR3 ligands were secreted by tissue fibroblasts and peripheral blood-derived mononuclear leukocytes in response to interferon-gamma (IFN-gamma) and Toll-like receptor (TLR) ligands. Subsequent purification and identification revealed the presence of...
6.
Protective role of IFN-gamma in collagen-induced arthritis conferred by inhibition of mycobacteria-induced granulocyte chemotactic protein-2 production
Kelchtermans H, Struyf S, De Klerck B, Mitera T, Alen M, Geboes L, et al.
J Leukoc Biol . 2007 Jan; 81(4):1044-53. PMID: 17200147
Mice with a disrupted IFN-gamma system are remarkably susceptible to experimental autoimmune diseases, such as collagen-induced arthritis (CIA), which rely on the use of CFA. The inflammatory lesions of these...
7.
TLR ligands and cytokines induce CXCR3 ligands in endothelial cells: enhanced CXCL9 in autoimmune arthritis
Loos T, Dekeyzer L, Struyf S, Schutyser E, Gijsbers K, Gouwy M, et al.
Lab Invest . 2006 Jul; 86(9):902-16. PMID: 16847431
CXC chemokines are potent attractants of neutrophil granulocytes, T cells or natural killer cells. Toll-like receptors (TLR) recognize microbial components and are also activated by endogenous molecules possibly implicated in...
8.
Synergistic induction of CXCL9 and CXCL11 by Toll-like receptor ligands and interferon-gamma in fibroblasts correlates with elevated levels of CXCR3 ligands in septic arthritis synovial fluids
Proost P, Verpoest S, Van de Borne K, Schutyser E, Struyf S, Put W, et al.
J Leukoc Biol . 2004 Mar; 75(5):777-84. PMID: 14996826
The synovial cavity constitutes the ideal stage to study the interplay between microbial Toll-like receptor (TLR) ligands and cytokines. Infiltrated leukocytes and synovial fibroblasts produce cytokine- and chemokine-induced proteases for...
9.
Microbial Toll-like receptor ligands differentially regulate CXCL10/IP-10 expression in fibroblasts and mononuclear leukocytes in synergy with IFN-gamma and provide a mechanism for enhanced synovial chemokine levels in septic arthritis
Proost P, Vynckier A, Mahieu F, Put W, Grillet B, Struyf S, et al.
Eur J Immunol . 2003 Oct; 33(11):3146-53. PMID: 14579283
The CXC chemokine IFN-gamma-inducible protein-10 (IP-10/CXCL10) activates CXC chemokine receptor 3 (CXCR3) and attracts activated T cells and natural killer cells. Peripheral blood mononuclear cells (PBMC) produce low but significant...
10.
The CXC chemokine GCP-2/CXCL6 is predominantly induced in mesenchymal cells by interleukin-1beta and is down-regulated by interferon-gamma: comparison with interleukin-8/CXCL8
Wuyts A, Struyf S, Gijsbers K, Schutyser E, Put W, Conings R, et al.
Lab Invest . 2003 Jan; 83(1):23-34. PMID: 12533683
Human granulocyte chemotactic protein-2 (GCP-2)/CXCL6 is a CXC chemokine that functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell-derived neutrophil...