Ghislain Opdenakker
Overview
Explore the profile of Ghislain Opdenakker including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
286
Citations
8916
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Van Damme J, Struyf S, Proost P, Opdenakker G, Gouwy M
Int J Mol Sci
. 2025 Mar;
26(5).
PMID: 40076881
The acute phase response is a hallmark of all inflammatory reactions and acute phase reactants, such as C-reactive protein (CRP) and serum amyloid A (SAA) proteins, are among the most...
2.
Abu El-Asrar A, Nawaz M, Ahmad A, Siddiquei M, Allegaert E, Adyns L, et al.
Cells
. 2025 Jan;
14(2).
PMID: 39851513
The protease, a disintegrin and metalloproteinase with thrombospondin type 1 motif member 13 (ADAMTS13), known to cleave only the von Willebrand factor (VWF), has powerful regulatory effects on microvascular platelet...
3.
Pereira R, EzEldeen M, Ugarte-Berzal E, Vandooren J, Martens E, Gouwy M, et al.
Front Immunol
. 2024 Aug;
15:1359497.
PMID: 39156898
SDF-1/CXCL12 is a unique chemotactic factor with multiple functions on various types of precursor cells, all carrying the cognate receptor CXCR4. Whereas individual biological functions of SDF-1/CXCL12 have been well...
4.
Visser N, Herreman L, Vandooren J, Pereira R, Opdenakker G, Spelbrink R, et al.
J Mol Med (Berl)
. 2024 Feb;
102(4):521-536.
PMID: 38381158
Viruses critically rely on various proteases to ensure host cell entry and replication. In response to viral infection, the host will induce acute tissue inflammation pulled by granulocytes. Upon hyperactivation,...
5.
Abu El-Asrar A, Nawaz M, Ahmad A, Dillemans L, Siddiquei M, Allegaert E, et al.
Int J Mol Sci
. 2023 Nov;
24(21).
PMID: 37958563
We aimed to investigate the role of the CD40-CD40 ligand (CD40L) pathway in inflammation-mediated angiogenesis in proliferative diabetic retinopathy (PDR). We analyzed vitreous fluids and epiretinal fibrovascular membranes from PDR...
6.
Abu El-Asrar A, De Hertogh G, Allegaert E, Nawaz M, Abouelasrar Salama S, Gikandi P, et al.
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37686317
Inflammation and fibrosis are key features of proliferative vitreoretinal disorders. We aimed to define the macrophage phenotype and investigate the role of macrophage-myofibroblast transition (MMT) in the contribution to myofibroblast...
7.
Van Damme J, Opdenakker G, Van Damme S, Struyf S
Eur Cytokine Netw
. 2023 Jun;
34(1):1-9.
PMID: 37387364
Polyclonal antisera from patients have been at the basis of the description of autoimmune diseases and today monoclonal antibodies are widely used in the therapy of cancer and many inflammatory...
8.
Pereira R, EzEldeen M, Ugarte-Berzal E, Martens E, Malengier-Devlies B, Vandooren J, et al.
Front Immunol
. 2023 May;
14:1170153.
PMID: 37168862
Introduction: Wound healing is a complex process to restore homeostasis after injury and insufficient skin wound healing is a considerable problem in medicine. Whereas many attempts of regenerative medicine have...
9.
Grillet B, Pereira R, Van Damme J, El-Asrar A, Proost P, Opdenakker G
Nat Rev Rheumatol
. 2023 May;
19(6):363-377.
PMID: 37161083
Proteolysis of structural molecules of the extracellular matrix (ECM) is an irreversible post-translational modification in all arthropathies. Common joint disorders, including osteoarthritis and rheumatoid arthritis, have been associated with increased...
10.
Metzemaekers M, Malengier-Devlies B, Gouwy M, De Somer L, Cunha F, Opdenakker G, et al.
Med Res Rev
. 2023 Apr;
43(5):1537-1606.
PMID: 37036061
Neutrophils are powerful effector cells leading the first wave of acute host-protective responses. These innate leukocytes are endowed with oxidative and nonoxidative defence mechanisms, and play well-established roles in fighting...