William Y Tsang
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Explore the profile of William Y Tsang including associated specialties, affiliations and a list of published articles.
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25
Citations
1293
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Recent Articles
1.
Hossain D, Shih S, Xiao X, White J, Tsang W
J Cell Sci
. 2020 Jan;
133(4).
PMID: 31974111
The centrosome linker serves to hold the duplicated centrosomes together until they separate in late G2/early mitosis. Precisely how the linker is assembled remains an open question. In this study,...
2.
Hossain D, Tsang W
Results Probl Cell Differ
. 2019 Aug;
67:17-25.
PMID: 31435790
Acetylation is among the most prevalent posttranslational modifications in cells and regulates a number of physiological processes such as gene transcription, cell metabolism, and cell signaling. Although initially discovered on...
3.
Hossain D, Barbelanne M, Tsang W
Cell Mol Life Sci
. 2019 Jun;
77(1):195-212.
PMID: 31177295
During ciliogenesis, the mother centriole transforms into a basal body competent to nucleate a cilium. The mother centriole and basal body possess sub-distal appendages (SDAs) and basal feet (BF), respectively....
4.
Hossain D, Tsang W
Semin Cell Dev Biol
. 2018 Sep;
93:145-152.
PMID: 30213760
The primary cilium is a cellular antenna found on the surface of many eukaryotic cells, whose main role is to sense and transduce signals that regulate growth, development, and differentiation....
5.
Hossain D, Barbosa J, Cohen E, Tsang W
J Biol Chem
. 2018 May;
293(24):9448-9460.
PMID: 29724823
Viruses exploit the host cell machinery for their own profit. To evade innate immune sensing and promote viral replication, HIV type 1 (HIV-1) subverts DNA repair regulatory proteins and induces...
6.
Das A, Qian J, Tsang W
PLoS Genet
. 2017 May;
13(5):e1006791.
PMID: 28498859
Ciliogenesis is a fundamental biological process central to human health. Precisely how this process is coordinated with the cell cycle remains an open question. We report that nephrocystin-5 (NPHP5/IQCB1), a...
7.
Hossain D, Javadi Esfehani Y, Das A, Tsang W
EMBO Rep
. 2017 Mar;
18(4):632-644.
PMID: 28242748
The centrosome plays a critical role in various cellular processes including cell division and cilia formation, and deregulation of centrosome homeostasis is a hallmark feature of many human diseases. Here,...
8.
Jouan L, Bencheikh B, Daoud H, Dionne-Laporte A, Dobrzeniecka S, Spiegelman D, et al.
Eur J Hum Genet
. 2015 Jul;
24(4):607-10.
PMID: 26197979
Agenesis of the corpus callosum (ACC) is a common brain malformation which can be observed either as an isolated condition or as part of numerous congenital syndromes. Therefore, cognitive and...
9.
Barbelanne M, Hossain D, Chan D, Peranen J, Tsang W
Hum Mol Genet
. 2015 Jan;
24(8):2185-200.
PMID: 25552655
Proper functioning of cilia, hair-like structures responsible for sensation and locomotion, requires nephrocystin-5 (NPHP5) and a multi-subunit complex called the Bardet-Biedl syndrome (BBS)ome, but their precise relationship is not understood....
10.
Barbelanne M, Tsang W
Biomed Res Int
. 2014 Dec;
2014:547986.
PMID: 25548773
Autosomal recessive primary microcephaly (MCPH) is a rare hereditary neurodevelopmental disorder characterized by a marked reduction in brain size and intellectual disability. MCPH is genetically heterogeneous and can exhibit additional...