William R Sellers
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Explore the profile of William R Sellers including associated specialties, affiliations and a list of published articles.
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Articles
173
Citations
33905
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Recent Articles
1.
Chaturantabut S, Oliver S, Frederick D, Kim J, Robinson F, Sinopoli A, et al.
J Clin Invest
. 2025 Feb;
PMID: 40014401
Translocations involving FGFR2 gene fusions are common in cholangiocarcinoma and predict response to FGFR kinase inhibitors. However, response rates and durability are limited due to the emergence of resistance, typically...
2.
Jin C, Hunkeler M, Mulvaney K, Sellers W, Fischer E
J Biol Chem
. 2025 Jan;
301(2):108165.
PMID: 39793893
Protein arginine methyltransferase (PRMT) 5 is an essential arginine methyltransferase responsible for the majority of cellular symmetric dimethyl-arginine marks. PRMT5 uses substrate adaptors such as pICln, RIOK1, and COPR5 to...
3.
Fan A, Gadbois G, Huang H, Chaudhry C, Jiang J, Sigua L, et al.
Angew Chem Int Ed Engl
. 2024 Nov;
64(5):e202417272.
PMID: 39602499
Bifunctional molecules such as targeted protein degraders induce proximity to promote gain-of-function pharmacology. These powerful approaches have gained broad traction across academia and the pharmaceutical industry, leading to an intensive...
4.
Chaturantabut S, Oliver S, Frederick D, Kim J, Robinson F, Sinopoli A, et al.
bioRxiv
. 2024 Sep;
PMID: 39345400
Summary: We identify biparatopic FGFR2 antibodies that are effective against FGFR2 fusion driven cholangiocarcinoma.
5.
Greulich H, Chen T, Feng W, Janne P, Alvarez J, Zappaterra M, et al.
PLoS Med
. 2024 Sep;
21(9):e1004470.
PMID: 39284164
[This corrects the article DOI: 10.1371/journal.pmed.0020313.].
6.
Berger R, Febbo P, Majumder P, Zhao J, Mukherjee S, Signoretti S, et al.
Cancer Res
. 2024 Aug;
84(15):2561.
PMID: 39086315
No abstract available.
7.
Vijay V, Karisani N, Shi L, Hung Y, Vu P, Kattel P, et al.
bioRxiv
. 2024 Jul;
PMID: 39026794
Biliary tract cancers (BTCs) are a group of deadly malignancies encompassing intrahepatic and extrahepatic cholangiocarcinoma, gallbladder carcinoma, and ampullary carcinoma. Here, we present the integrative analysis of 63 BTC cell...
8.
Majumder P, Grisanzio C, OConnell F, Barry M, Brito J, Xu Q, et al.
Cancer Cell
. 2024 Jun;
42(6):1126.
PMID: 38866454
No abstract available.
9.
Huang H, Lumpkin R, Tsai R, Su S, Zhao X, Xiong Y, et al.
Nat Chem Biol
. 2024 Mar;
20(9):1227-1236.
PMID: 38514884
Protein ubiquitylation controls diverse processes within eukaryotic cells, including protein degradation, and is often dysregulated in disease. Moreover, small-molecule degraders that redirect ubiquitylation activities toward disease targets are an emerging...
10.
Chang L, Jung N, Atari A, Rodriguez D, Kesar D, Song T, et al.
Nat Genet
. 2024 Feb;
56(3):553.
PMID: 38396071
No abstract available.