William R Kirkpatrick
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Explore the profile of William R Kirkpatrick including associated specialties, affiliations and a list of published articles.
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49
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1183
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Recent Articles
11.
Wiederhold N, Najvar L, Fothergill A, McCarthy D, Bocanegra R, Olivo M, et al.
Antimicrob Agents Chemother
. 2014 Oct;
59(1):690-2.
PMID: 25331706
The in vitro and in vivo activity of the inositol acyltransferase inhibitor E1210 was evaluated against echinocandin-resistant Candida albicans. E1210 demonstrated potent in vitro activity, and in mice with invasive...
12.
Jambunathan K, Watson D, Najvar L, Wiederhold N, Kirkpatrick W, Patterson T, et al.
Med Mycol
. 2013 Jan;
51(6):592-602.
PMID: 23356446
Improved diagnostics are needed to detect invasive pulmonary aspergillosis, a life-threatening infection caused by the pathogenic fungus Aspergillus fumigatus. We are investigating secreted fungal proteases as novel biomarkers for the...
13.
Westbrook S, Kirkpatrick W, Wiederhold N, Freytes C, Toro J, Patterson T, et al.
Oral Surg Oral Med Oral Pathol Oral Radiol
. 2013 Jan;
115(3):354-8.
PMID: 23312542
Objective: We monitored the epidemiology and microbiology of oral yeast colonization in patients undergoing hemopoietic progenitor cell transplantation (HPCT) to examine associations between yeast colonization and oral mucositis. Study Design:...
14.
Wiederhold N, Najvar L, Bocanegra R, Kirkpatrick W, Patterson T, Thornton C
J Clin Microbiol
. 2012 Nov;
51(2):459-65.
PMID: 23175252
Interest in lateral-flow devices (LFDs) as potential point-of-care assays for the diagnosis of infectious diseases has increased. Our objective was to evaluate the interlaboratory and interstudy reproducibility and the effects...
15.
Wiederhold N, Najvar L, Bocanegra R, Kirkpatrick W, Sorrell T, Patterson T
Antimicrob Agents Chemother
. 2012 Nov;
57(2):745-50.
PMID: 23165465
Miltefosine is an alkyl phosphocholine with good oral bioavailability and in vitro activity against Cryptococcus species that has gained interest as an additional agent for cryptococcal infections. Our objective was...
16.
Patel P, Erlandsen J, Kirkpatrick W, Berg D, Westbrook S, Louden C, et al.
AIDS Res Treat
. 2012 Sep;
2012:262471.
PMID: 22970352
The impact of antiretroviral therapy (ART) on opportunistic conditions in HIV patients continues to evolve. We specifically studied the changing epidemiology of oropharyngeal candidiasis (OPC) in 215 HIV/AIDS patients. Status...
17.
Thompson 3rd G, Wiederhold N, Najvar L, Bocanegra R, Kirkpatrick W, Graybill J, et al.
J Antimicrob Chemother
. 2012 Mar;
67(6):1432-8.
PMID: 22378683
Objectives: Meningoencephalitis caused by Cryptococcus gattii is associated with significant morbidity and the need for aggressive therapy, and often necessitates neurosurgical intervention. We adapted a previously described murine model of...
18.
Hooper D, Bolton V, Sutton J, Guilford F, Straus D, Najvar L, et al.
Int J Mol Sci
. 2012 Feb;
13(1):726-736.
PMID: 22312282
In this study we pursued a diagnostic target in Aspergillus fumigatus (AF) by using qualitative Realtime PCR combined with proprietary DNA primers and a hydrolysis probe specific for this fungal...
19.
Kirkpatrick W, Najvar L, Vallor A, Wiederhold N, Bocanegra R, Pfeiffer J, et al.
J Antimicrob Chemother
. 2012 Jan;
67(4):970-6.
PMID: 22240402
Objectives: Amphotericin B inhalation powder (ABIP) is a novel dry-powder amphotericin B formulation that is directly delivered to the lung, resulting in elevated lung tissue drug concentrations of this polyene....
20.
Lengerova M, Kocmanova I, Racil Z, Hrncirova K, Pospisilova S, Mayer J, et al.
J Clin Microbiol
. 2011 Dec;
50(3):602-8.
PMID: 22189110
We developed and assessed the diagnostic value of a novel quantitative nested real-time (QNRT) PCR assay targeting the internal transcribed spacer region of ribosomal DNA (rDNA) in a guinea pig...