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Thomas F Patterson

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Articles 191
Citations 17275
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Recent Articles
1.
Cornely O, Sprute R, Bassetti M, Chen S, Groll A, Kurzai O, et al.
Lancet Infect Dis . 2025 Feb; PMID: 39956121
Candida species are the predominant cause of fungal infections in patients treated in hospital, contributing substantially to morbidity and mortality. Candidaemia and other forms of invasive candidiasis primarily affect patients...
2.
Vernon S, Zheng T, Do H, Marconi V, Jason L, Singer N, et al.
J Gen Intern Med . 2025 Jan; PMID: 39804551
Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) may occur after infection. How often people develop ME/CFS after SARS-CoV-2 infection is unknown. Objective: To determine the incidence and prevalence of post-COVID-19 ME/CFS...
3.
Geng L, Erlandson K, Hornig M, Letts R, Selvaggi C, Ashktorab H, et al.
JAMA . 2024 Dec; 333(8):694-700. PMID: 39693079
Importance: Classification of persons with long COVID (LC) or post-COVID-19 condition must encompass the complexity and heterogeneity of the condition. Iterative refinement of the classification index for research is needed...
4.
Wiederhold N, Patterson H, Ferrer D, Garcia V, Thompson G, Patterson T
Antimicrob Agents Chemother . 2024 Nov; 69(1):e0098824. PMID: 39570032
We evaluated the activity of olorofim against species. Olorofim demonstrated potent activity against all isolates tested with a minimum inhibitory concentration (MIC) range ≤0.008-0.06 µg/mL and geometric mean MIC of...
5.
Wiederhold N, Najvar L, Jaramillo R, Olivo M, Larwood D, Patterson T
Microbiol Spectr . 2024 Aug; 12(10):e0135624. PMID: 39162491
Importance: species are endemic fungi that are capable of causing disease in patients with various comorbidities, as well as in otherwise healthy individuals. Treatment options for coccidioidomycosis are suboptimal, as...
6.
Erlandson K, Geng L, Selvaggi C, Thaweethai T, Chen P, Erdmann N, et al.
Ann Intern Med . 2024 Aug; 177(9):1209-1221. PMID: 39133923
Background: There are currently no validated clinical biomarkers of postacute sequelae of SARS-CoV-2 infection (PASC). Objective: To investigate clinical laboratory markers of SARS-CoV-2 and PASC. Design: Propensity score-weighted linear regression...
7.
Gebremariam T, Alkhazraji S, Gu Y, Najvar L, Borroto-Esoda K, Patterson T, et al.
Antimicrob Agents Chemother . 2024 Apr; 68(5):e0154523. PMID: 38557112
Ibrexafungerp (formerly SCY-078) is the first member of the triterpenoid class that prevents the synthesis of the fungal cell wall polymer β-(1,3)-D-glucan by inhibiting the enzyme glucan synthase. We evaluated...
8.
Young J, Andes D, Ardura M, Arrieta A, Bow E, Chandrasekar P, et al.
Open Forum Infect Dis . 2024 Mar; 11(3):ofae082. PMID: 38481428
The epidemiology of invasive aspergillosis (IA) is evolving. To define the patient groups who will most likely benefit from primary or secondary prophylaxis, particularly those whose medical conditions and IA...
9.
Maji A, Soutar C, Zhang J, Lewandowska A, Uno B, Yan S, et al.
Nature . 2023 Nov; 623(7989):1079-1085. PMID: 37938782
Decades of previous efforts to develop renal-sparing polyene antifungals were misguided by the classic membrane permeabilization model. Recently, the clinically vital but also highly renal-toxic small-molecule natural product amphotericin B...
10.
Ajetunmobi O, Wall G, Vidal Bonifacio B, Martinez Delgado L, Chaturvedi A, Najvar L, et al.
J Fungi (Basel) . 2023 Sep; 9(9). PMID: 37754987
Candidiasis is one of the most frequent nosocomial infections affecting an increasing number of at-risk patients. remains the most frequent causative agent of candidiasis, but, in the last decade, has...