William R Ferrell
Overview
Explore the profile of William R Ferrell including associated specialties, affiliations and a list of published articles.
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37
Citations
995
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Recent Articles
11.
Ferrell W, Kelso E, Lockhart J, Plevin R, McInnes I
Ann Rheum Dis
. 2010 Jun;
69(11):2051-4.
PMID: 20584806
Objective: Osteoarthritis is a global clinical challenge for which no effective disease-modifying agents currently exist. This study identified protease-activated receptor 2 (PAR-2) as a novel pathogenic mechanism and potential therapeutic...
12.
Milner J, Patel A, Davidson R, Swingler T, Desilets A, Young D, et al.
Arthritis Rheum
. 2010 May;
62(7):1955-66.
PMID: 20506309
Objective: Increasing evidence implicates serine proteinases in pathologic tissue turnover. The aim of this study was to assess the role of the transmembrane serine proteinase matriptase in cartilage destruction in...
13.
Riley S, Gibbs T, Ferrell W, Nelson P, Smith W, Murphy M
Med Teach
. 2009 Nov;
31(10):895-902.
PMID: 19877861
Background: Student Selected Components (SSCs) are an established feature of UK undergraduate medical curricula that offer students choice. They represent a large investment in time and resources. Although programmes vary...
14.
Kanagalingam M, Nelson S, Freeman D, Ferrell W, Cherry L, Lowe G, et al.
Atherosclerosis
. 2008 Nov;
205(1):244-50.
PMID: 19022445
Objective: Offspring and maternal birthweight are inversely associated with maternal cardiovascular disease. However, whether established or putative novel cardiovascular risk factors including vascular and metabolic function are disrupted in women...
15.
Riley S, Ferrell W, Gibbs T, Murphy M, Cairns W, Smith S
Med Teach
. 2008 Jun;
30(4):370-6.
PMID: 18569657
Background: Student selected components (SSCs) represent a significant component of medical curricula in the UK and a new approach in medical education. Despite the prominence given to SSCs by the...
16.
Mackinnon B, Deighan C, Ferrell W, Sattar N, Fox J
Nephron Clin Pract
. 2008 May;
109(1):c40-7.
PMID: 18509248
Background: Cardiovascular disease is the commonest cause of mortality among patients with end-stage renal disease. Endothelial function and inflammation have previously been shown to be abnormal among such individuals, and...
17.
Ferrell W, Tennant N, Baxendale R, Kusel M, Sturrock R
Arthritis Rheum
. 2007 Oct;
57(7):1329-33.
PMID: 17907144
No abstract available.
18.
Jadhav S, Sattar N, Petrie J, Cobbe S, Ferrell W
J Cardiovasc Pharmacol
. 2007 Sep;
50(3):343-9.
PMID: 17878765
Interrogation of peripheral vascular function is increasingly recognized as a noninvasive surrogate marker for coronary vascular function and carries with it important prognostic information regarding future cardiovascular risk. Laser Doppler...
19.
Balmain S, Padmanabhan N, Ferrell W, Morton J, McMurray J
Eur J Heart Fail
. 2007 Jul;
9(9):865-71.
PMID: 17644472
Background: Up to 50% of patients with the clinical syndrome of heart failure have preserved left ventricular systolic function (HF-PSF). These patients may have abnormalities of ventriculo-vascular coupling, due to...
20.
McIntosh K, Plevin R, Ferrell W, Lockhart J
Curr Opin Pharmacol
. 2007 Mar;
7(3):334-8.
PMID: 17369094
Proteinase-activated receptors are a family of seven-transmembrane G-protein-coupled receptors. Activation of PARs is initiated through cleavage of the N-terminus, unmasking a tethered ligand that can then interact with the receptor...