William OConnor Jr
Overview
Explore the profile of William OConnor Jr including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
17
Citations
1867
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Akhtar K, Hirschstein Z, Stefanelli A, Iannilli E, Srinivasan A, Barenboim L, et al.
Exp Physiol
. 2021 Jan;
106(4):1038-1060.
PMID: 33512049
New Findings: What is the central question of this study? Does peripheral non-invasive focused ultrasound targeted to the celiac plexus improve inflammatory bowel disease? What is the main finding and...
2.
Walrath T, Malizia R, Zhu X, Sharp S, DSouza S, Lopez-Soler R, et al.
Am J Physiol Gastrointest Liver Physiol
. 2019 Dec;
318(3):G479-G489.
PMID: 31790273
During intestinal inflammation, immature cells within the intestinal crypt are called upon to replenish lost epithelial cell populations, promote tissue regeneration, and restore barrier integrity. Inflammatory mediators including T1/T17-associated cytokines...
3.
Sharp S, Malizia R, Walrath T, DSouza S, Booth C, Kartchner B, et al.
Gene
. 2018 Aug;
677:299-307.
PMID: 30121380
Chronic intestinal inflammation predisposes patients with Inflammatory Bowel Disease (IBD) to Colitis-Associated Cancer (CAC). In the setting of chronic inflammation, microsatellite instability (MSI) results from early loss of DNA damage...
4.
Huber S, Gagliani N, OConnor Jr W, Geginat J, Caprioli F
Mediators Inflamm
. 2017 Mar;
2017:7083153.
PMID: 28250577
No abstract available.
5.
Busman-Sahay K, Walrath T, Huber S, OConnor Jr W
J Leukoc Biol
. 2014 Dec;
97(3):499-510.
PMID: 25548251
In the 2 decades since its discovery, IL-17A has become appreciated for mounting robust, protective responses against bacterial and fungal pathogens. When improperly regulated, however, IL-17A can play a profoundly...
6.
OConnor Jr W, Esplugues E, Huber S
J Immunol Res
. 2014 May;
2014:936270.
PMID: 24872959
No abstract available.
7.
Califano D, Sweeney K, Le H, VanValkenburgh J, Yager E, OConnor Jr W, et al.
J Clin Invest
. 2013 Dec;
124(1):174-87.
PMID: 24316973
Naive T helper cells differentiate into functionally distinct effector subsets that drive specialized immune responses. Recent studies indicate that some of the effector subsets have plasticity. Here, we used an...
8.
Huber S, Gagliani N, Zenewicz L, Huber F, Bosurgi L, Hu B, et al.
Nature
. 2012 Oct;
491(7423):259-63.
PMID: 23075849
Chronic mucosal inflammation and tissue damage predisposes patients to the development of colorectal cancer. This association could be explained by the hypothesis that the same factors and pathways important for...
9.
Esplugues E, Huber S, Gagliani N, Hauser A, Town T, Wan Y, et al.
Nature
. 2011 Jul;
475(7357):514-8.
PMID: 21765430
Interleukin (IL)-17-producing T helper cells (T(H)17) are a recently identified CD4(+) T cell subset distinct from T helper type 1 (T(H)1) and T helper type 2 (T(H)2) cells. T(H)17 cells...
10.
Kamanaka M, Huber S, Zenewicz L, Gagliani N, Rathinam C, OConnor Jr W, et al.
J Exp Med
. 2011 Apr;
208(5):1027-40.
PMID: 21518800
The role of direct IL-10 signaling in different T cell subsets is not well understood. To address this, we generated transgenic mice expressing a dominant-negative IL-10 receptor specifically in T...