William J Drury 3rd
Overview
Explore the profile of William J Drury 3rd including associated specialties, affiliations and a list of published articles.
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14
Citations
1284
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Recent Articles
1.
Cook B, Archbold J, Nasr K, Girmay S, Goldstein S, Li P, et al.
Mol Imaging Biol
. 2022 Jun;
24(6):940-949.
PMID: 35655109
Purpose: The treatment of complex neurological diseases often requires the administration of large therapeutic drugs, such as antisense oligonucleotide (ASO), by lumbar puncture into the intrathecal space in order to...
2.
Noisier A, Johansson M, Knerr L, Hayes M, Drury 3rd W, Valeur E, et al.
Angew Chem Int Ed Engl
. 2019 Oct;
58(52):19096-19102.
PMID: 31609503
The late-stage functionalization (LSF) of peptides represents a valuable strategy for the design of potent peptide pharmaceuticals by enabling rapid exploration of chemical diversity and offering novel opportunities for peptide...
3.
Gopalakrishnan R, Frolov A, Knerr L, Drury 3rd W, Valeur E
J Med Chem
. 2016 Jul;
59(21):9599-9621.
PMID: 27362955
Over the past decade, foldamers have progressively emerged as useful architectures to mimic secondary structures of proteins. Peptidic foldamers, consisting of various amino acid based backbones, have been the most...
4.
Beck D, Narendra V, Drury 3rd W, Casey R, Jansen P, Yuan Z, et al.
J Proteome Res
. 2014 Oct;
13(12):6135-43.
PMID: 25311790
Accurate and sensitive detection of protein-protein and protein-RNA interactions is key to understanding their biological functions. Traditional methods to identify these interactions require cell lysis and biochemical manipulations that exclude...
5.
Voigt P, LeRoy G, Drury 3rd W, Zee B, Son J, Beck D, et al.
Cell
. 2012 Oct;
151(1):181-93.
PMID: 23021224
Mononucleosomes, the basic building blocks of chromatin, contain two copies of each core histone. The associated posttranslational modifications regulate essential chromatin-dependent processes, yet whether each histone copy is identically modified...
6.
Dancy B, Ming S, Papazyan R, Jelinek C, Majumdar A, Sun Y, et al.
J Am Chem Soc
. 2012 Feb;
134(11):5138-48.
PMID: 22352831
Reversible lysine acetylation and methylation regulate the function of a wide variety of proteins, including histones. Here, we have synthesized azalysine-containing peptides in acetylated and unacetylated forms as chemical probes...
7.
Sims 3rd R, Rojas L, Beck D, Bonasio R, Schuller R, Drury 3rd W, et al.
Science
. 2011 Apr;
332(6025):99-103.
PMID: 21454787
The carboxy-terminal domain (CTD) of RNA polymerase II (RNAPII) in mammals undergoes extensive posttranslational modification, which is essential for transcriptional initiation and elongation. Here, we show that the CTD of...
8.
Li Y, Trojer P, Xu C, Cheung P, Kuo A, Drury 3rd W, et al.
J Biol Chem
. 2009 Oct;
284(49):34283-95.
PMID: 19808676
The NSD (nuclear receptor SET domain-containing) family of histone lysine methyltransferases is a critical participant in chromatin integrity as evidenced by the number of human diseases associated with the aberrant...
9.
Margueron R, Justin N, Ohno K, Sharpe M, Son J, Drury 3rd W, et al.
Nature
. 2009 Sep;
461(7265):762-7.
PMID: 19767730
Polycomb group proteins have an essential role in the epigenetic maintenance of repressive chromatin states. The gene-silencing activity of the Polycomb repressive complex 2 (PRC2) depends on its ability to...
10.
Szewczuk L, Tarrant M, Sample V, Drury 3rd W, Zhang J, Cole P
Biochemistry
. 2008 Sep;
47(39):10407-19.
PMID: 18771288
Serotonin N-acetyltransferase [arylalkylamine N-acetyltransferase (AANAT)] is a key circadian rhythm enzyme that drives the nocturnal production of melatonin in the pineal. Prior studies have suggested that its light and diurnal...