William G Kelly
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Explore the profile of William G Kelly including associated specialties, affiliations and a list of published articles.
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31
Citations
1528
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Recent Articles
1.
Maehigashi T, Lim C, Wade L, Bowen N, Knecht K, Alvarez N, et al.
J Biol Chem
. 2023 Aug;
299(9):105148.
PMID: 37567474
Mutations in sterile alpha motif domain and histidine-aspartate domain-containing protein 1 (SAMHD1) are found in a neurodevelopmental disorder, Aicardi-Goutières syndrome, and cancers, and SAMHD1, which is a deoxynucleoside triphosphate (dNTP)...
2.
Fielder S, Kent T, Ling H, Gleason E, Kelly W
Genetics
. 2021 Nov;
220(1).
PMID: 34788833
The dynein motor complex is thought to aid in homolog pairing in many organisms by moving chromosomes within the nuclear periphery to promote and test homologous interactions. This precedes synaptonemal...
3.
Ahn J, Rechtsteiner A, Strome S, Kelly W
PLoS Genet
. 2017 Jun;
13(5):e1006821.
PMID: 28562665
[This corrects the article DOI: 10.1371/journal.pgen.1006227.].
4.
Myrick D, Christopher M, Scott A, Simon A, Donlin-Asp P, Kelly W, et al.
PLoS One
. 2017 May;
12(5):e0177473.
PMID: 28498828
The proper regulation of spermatogenesis is crucial to ensure the continued production of sperm and fertility. Here, we investigated the function of the H3K4me2 demethylase KDM1A/LSD1 during spermatogenesis in developing...
5.
Ahn J, Rechsteiner A, Strome S, Kelly W
PLoS Genet
. 2016 Aug;
12(8):e1006227.
PMID: 27541139
The elongation phase of transcription by RNA Polymerase II (Pol II) involves numerous events that are tightly coordinated, including RNA processing, histone modification, and chromatin remodeling. RNA splicing factors are...
6.
Kelly W
Dev Cell
. 2014 Nov;
31(2):142-4.
PMID: 25373774
Epigenetic memory stably maintains and transmits information during genome replication. Recently in Science, Gaydos et al. (2014) show that repressive chromatin marks exhibit transgenerational stability in the absence of chromatin-modifying...
7.
Bowman E, Kelly W
Nucleus
. 2014 Jun;
5(3):224-36.
PMID: 24879308
The transition between initiation and productive elongation during RNA Polymerase II (Pol II) transcription is a well-appreciated point of regulation across many eukaryotes. Elongating Pol II is modified by phosphorylation...
8.
Li T, Kelly W
Nucleic Acids Res
. 2014 Apr;
42(9):5567-81.
PMID: 24682813
The hermaphrodite germline of Caenorhabditis elegans initially engages in spermatogenesis and then switches to oogenesis during late stages of larval development. TRA-1, a member of the Ci/Gli family of transcriptional...
9.
Kelly W
Epigenetics Chromatin
. 2014 Apr;
7(1):6.
PMID: 24678826
Epigenetic mechanisms create variably stable changes in gene expression through the establishment of heritable states of chromatin architecture. While many epigenetic phenomena are, by definition, heritably passed through cell division...
10.
Strome S, Kelly W, Ercan S, Lieb J
Cold Spring Harb Perspect Biol
. 2014 Mar;
6(3).
PMID: 24591522
Dosage compensation, which regulates the expression of genes residing on the sex chromosomes, has provided valuable insights into chromatin-based mechanisms of gene regulation. The nematode Caenorhabditis elegans has adopted various...