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William F Maragos

Explore the profile of William F Maragos including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 638
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Recent Articles
1.
Korde A, Maragos W
Mitochondrion . 2021 Apr; 59:76-82. PMID: 33894358
Our laboratory has demonstrated that functional N-methyl-d-aspartate-like receptors are present on neuronal mitochondria (NMDA). This novel site gates the influx of Ca and causes a several-fold increase in ATP levels....
2.
Schier C, Marks W, Paris J, Barbour A, McLane V, Maragos W, et al.
J Neurosci . 2017 May; 37(23):5758-5769. PMID: 28473642
Despite marked regional differences in HIV susceptibility within the CNS, there has been surprisingly little exploration into the differential vulnerability among neuron types and the circuits they underlie. The dorsal...
3.
Korde A, Maragos W
Neurosci Lett . 2016 May; 623:47-51. PMID: 27132085
N-methyl-d-aspartate (NMDA) receptors have long been known to be associated with the plasma membrane, providing a channel for the passage of extracellular Ca(2+) into the cytosol during synaptic transmission. Recent...
4.
Korde A, Maragos W
J Biol Chem . 2012 Aug; 287(42):35192-35200. PMID: 22918829
NMDA ionotropic glutamate receptors gate the cytoplasmic influx of calcium, which may, depending on the intensity of the stimulus, subserve either normal synaptic communication or cell death. We demonstrate that...
5.
Theodore S, Cass W, Dwoskin L, Maragos W
Synapse . 2012 Apr; 66(8):755-7. PMID: 22517264
No abstract available.
6.
Berman J, Carson M, Chang L, Cox B, Fox H, Gonzalez R, et al.
J Neuroimmune Pharmacol . 2007 Nov; 1(4):351-99. PMID: 18040811
Neurological complications of human immunodeficiency virus (HIV) infection are a public health problem despite the availability of active antiretroviral therapies. The neuropathogenesis of HIV infection revolves around a complex cascade...
7.
Korde A, Pettigrew L, Craddock S, Pocernich C, Waldmeier P, Maragos W
J Neurotrauma . 2007 May; 24(5):895-908. PMID: 17518543
Cerebral ischemia followed by reperfusion activates numerous pathways that lead to cell death. One such pathway involves the release of large quantities of the excitatory amino acid glutamate into the...
8.
Pandya J, Pauly J, Nukala V, Sebastian A, Day K, Korde A, et al.
J Neurotrauma . 2007 May; 24(5):798-811. PMID: 17518535
Following experimental traumatic brain injury (TBI), a rapid and significant necrosis occurs at the site of injury which coincides with significant mitochondrial dysfunction. The present study is driven by the...
9.
Theodore S, Cass W, Nath A, Maragos W
Curr HIV Res . 2007 May; 5(3):301-13. PMID: 17504172
HIV-1 infection with concurrent methamphetamine (MA) abuse results in exacerbated neurodegenerative changes and rapid progression of a form of sub-cortical dementia termed HIV-1 associated dementia (HAD). A notable feature of...
10.
Hauser K, El-Hage N, Stiene-Martin A, Maragos W, Nath A, Persidsky Y, et al.
J Neurochem . 2006 Dec; 100(3):567-86. PMID: 17173547
Neuronal dysfunction and degeneration are ultimately responsible for the neurocognitive impairment and dementia manifest in neuroAIDS. Despite overt neuronal pathology, HIV-1 does not directly infect neurons; rather, neuronal dysfunction or...