Patrick G Sullivan
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Explore the profile of Patrick G Sullivan including associated specialties, affiliations and a list of published articles.
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Articles
147
Citations
5546
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Recent Articles
1.
Constantino N, Carroll C, Williams H, Vekaria H, Yuede C, Saito K, et al.
Proc Natl Acad Sci U S A
. 2025 Feb;
122(8):e2416578122.
PMID: 39964713
Metabolism plays a key role in the maintenance of sleep/wake states. Brain lactate fluctuations are a biomarker of sleep/wake transitions, where increased interstitial fluid (ISF) lactate levels are associated with...
2.
Ahmed A, Gallegos Z, Dinar M, Sullivan P, DeRouchey J, Patel S, et al.
J Biomed Mater Res B Appl Biomater
. 2025 Feb;
113(2):e35537.
PMID: 39907118
Traumatic spinal cord injury (SCI) presents a significant medical challenge due to its intricate nature and treatment complexities. SCI can cause physical impairments by affecting neural and motor functions as...
3.
Velmurugan G, Vekaria H, Patel S, Sullivan P, Hubbard W
J Cereb Blood Flow Metab
. 2024 Dec;
:271678X241306054.
PMID: 39668588
Intercellular mitochondrial transfer (IMT) is an intriguing biological phenomenon where mitochondria are transferred between different cells and notably, cell types. IMT is physiological, occurring in normal conditions, but also is...
4.
Sims S, Frazier H, Case S, Lin R, Trosper J, Vekaria H, et al.
NPJ Metab Health Dis
. 2024 Nov;
2(1):33.
PMID: 39524535
Energy flow within cellular elements of the brain is a well-orchestrated, tightly regulated process, however, details underlying these functions at the single-cell level are still poorly understood. Studying hypometabolism in...
5.
Crivelli S, Quadri Z, Elsherbini A, Vekaria H, Sullivan P, Zhi W, et al.
ASN Neuro
. 2024 Nov;
16(1):2404367.
PMID: 39499163
During pathogenesis of Alzheimer's disease (AD), mitochondria suffer alterations that lead to low energy production and reactive oxygen species formation. However, the mechanism of impaired mitochondria homeostasis in AD is...
6.
Kalimon O, Vekaria H, Prajapati P, Short S, Hubbard W, Sullivan P
Life (Basel)
. 2024 Aug;
14(8).
PMID: 39202703
Current literature finds females have improved outcomes over their male counterparts after severe traumatic brain injury (TBI), while the opposite seems to be true for mild TBI. This begs the...
7.
Vekaria H, Kalimon O, Prajapati P, Velmurugan G, Sullivan P
Front Mol Biosci
. 2024 Jul;
11:1378536.
PMID: 38983247
Mitochondrial function analysis is a well-established method used in preclinical and clinical investigations to assess pathophysiological changes in various disease states, including traumatic brain injury (TBI). Although there are multiple...
8.
Sanganahalli B, Mihailovic J, Vekaria H, Coman D, Yackzan A, Flemister A, et al.
J Cereb Blood Flow Metab
. 2024 Jun;
44(10):1745-1758.
PMID: 38879800
Apolipoprotein ε4 (APOE4) carriers develop brain metabolic dysfunctions decades before the onset of Alzheimer's disease (AD). A goal of the study is to identify if rapamycin, an inhibitor for the...
9.
Hubbard W, Velmurugan G, Sullivan P
Neurochem Int
. 2024 Feb;
174:105680.
PMID: 38311216
Mitostasis, the maintenance of healthy mitochondria, plays a critical role in brain health. The brain's high energy demands and reliance on mitochondria for energy production make mitostasis vital for neuronal...
10.
Latham C, Balawender P, Thomas N, Keeble A, Brightwell C, Ismaeel A, et al.
Free Radic Biol Med
. 2023 Dec;
212:191-198.
PMID: 38154571
Oxidative stress has been implicated in the etiology of skeletal muscle weakness following joint injury. We investigated longitudinal patient muscle samples following knee injury (anterior cruciate ligament tear). Following injury,...