William C Knowler
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Explore the profile of William C Knowler including associated specialties, affiliations and a list of published articles.
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332
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21545
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Recent Articles
1.
Munshi M, Venditti E, Tjaden A, Knowler W, Boyko E, Middelbeek R, et al.
Front Public Health
. 2025 Jan;
12():1470035.
PMID: 39744353
Objectives: Type 2 diabetes (T2D) and prediabetes are associated with poor walking endurance, a marker of physical function. We aimed to examine the long-term effects of metformin or intensive lifestyle...
2.
Arreola E, Coonrod D, Roy Choudhury S, Knowler W, Hoskin M, Wasak D, et al.
BMC Public Health
. 2024 Sep;
24(1):2661.
PMID: 39343891
Background: The prevalence of childhood obesity and diabetes continues to rise in the United States (US), especially among minority populations. The objective of the Early Tracking of Childhood Health Determinants...
3.
Knowler W, Chen H, Bahnson J, Kahn S, Lewis C, Nathan D, et al.
BMJ Open Diabetes Res Care
. 2024 May;
12(3).
PMID: 38816203
Introduction: The Look AHEAD randomized clinical trial reported that an 8-year intensive lifestyle intervention (ILI) compared with diabetes support and education (DSE) in adults aged 45-76 years with type 2...
4.
Billings L, Jablonski K, Pan Q, Florez J, Franks P, Goldberg R, et al.
Diabetes
. 2024 May;
73(8):1352-1360.
PMID: 38758294
Article Highlights:
5.
Shapiro A, Tjaden A, Edelstein S, Kahn S, Srikanthan P, Knowler W, et al.
J Diabetes Complications
. 2024 May;
38(6):108764.
PMID: 38701667
Objective: Dysglycemia is a significant risk factor for cognitive impairment. However, which pathophysiologic determinant(s) of dysglycemia, impaired insulin sensitivity (ISens) or the islet β-cell's response (IResp), contribute to poorer cognitive...
6.
Williams R, Hanson R, Peters B, Kearns K, Knowler W, Bogardus C, et al.
Diabetes
. 2024 Mar;
73(6):1002-1011.
PMID: 38530923
Article Highlights:
7.
Lee C, Ciarleglio A, Edelstein S, Crandall J, Dabelea D, Goldberg R, et al.
Diabetes Care
. 2024 Mar;
47(5):810-817.
PMID: 38502874
Objective: To assess associations between distal symmetric polyneuropathy (DSPN) and Diabetes Prevention Program (DPP) treatment groups, diabetes status or duration, and cumulative glycemic exposure approximately 21 years after DPP randomization....
8.
Arreola E, Knowler W, Baier L, Hanson R
BMJ Open Diabetes Res Care
. 2024 Jan;
11(6).
PMID: 38164708
Introduction: The gene regulates insulin secretion and plays a critical role in glucose homeostasis. The effects of an R1420H loss-of-function variant on beta-cell function, incidence of type 2 diabetes, and...
9.
Braxton M, Nwabichie E, Diaz M, Lish E, Ayers S, Williams A, et al.
Contemp Clin Trials
. 2023 Oct;
135:107361.
PMID: 37852533
Background: Latino families are disproportionately affected by type 2 diabetes (T2D) and lifestyle intervention is the first-line approach for preventing T2D. The purpose of this study is to test the...
10.
Molitch M, Tripputi M, Levey A, Crandall J, Dabelea D, Herman W, et al.
J Diabetes Complications
. 2023 Aug;
37(9):108556.
PMID: 37607422
Aims: We analyzed the incidence of kidney disease in the Diabetes Prevention Program Outcomes Study (DPPOS) by originally randomized treatment group assignment: Intensive Lifestyle (ILS), Metformin (MET) or Placebo (PLB)....