Wilhelm Bone
Overview
Explore the profile of Wilhelm Bone including associated specialties, affiliations and a list of published articles.
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Snapshot
Snapshot
Articles
9
Citations
128
Followers
0
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Related Specialties
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Recent Articles
1.
Ter Laak A, Hillig R, Ferrara S, Korr D, Barak N, Lienau P, et al.
J Med Chem
. 2024 Oct;
67(21):19282-19303.
PMID: 39450890
KAT6A and KAT6B genes are two closely related lysine acetyltransferases that transfer an acetyl group from acetyl coenzyme A (AcCoA) to lysine residues of target histone substrates, hence playing a...
2.
Graham K, Lienau P, Bader B, Prechtl S, Naujoks J, Lesche R, et al.
Cell Chem Biol
. 2024 Mar;
31(7):1247-1263.e16.
PMID: 38537632
This study describes the identification and target deconvolution of small molecule inhibitors of oncogenic Yes-associated protein (YAP1)/TAZ activity with potent anti-tumor activity in vivo. A high-throughput screen (HTS) of 3.8...
3.
Panknin O, Wagenfeld A, Bone W, Bender E, Nowak-Reppel K, Fernandez-Montalvan A, et al.
J Med Chem
. 2020 Sep;
63(20):11854-11881.
PMID: 32960053
The growth of uterine fibroids is sex hormone-dependent and commonly associated with highly incapacitating symptoms. Most treatment options consist of the control of these hormonal effects, ultimately blocking proliferative estrogen...
4.
Lucking U, Wortmann L, Wengner A, Lefranc J, Lienau P, Briem H, et al.
J Med Chem
. 2020 Jun;
63(13):7293-7325.
PMID: 32502336
The ATR kinase plays a key role in the DNA damage response by activating essential signaling pathways of DNA damage repair, especially in response to replication stress. Because DNA damage...
5.
Siemeister G, Mengel A, Fernandez-Montalvan A, Bone W, Schroder J, Zitzmann-Kolbe S, et al.
Clin Cancer Res
. 2018 Nov;
25(4):1404-1414.
PMID: 30429199
Purpose: The catalytic function of BUB1 is required for chromosome arm resolution and positioning of the chromosomal passenger complex for resolution of spindle attachment errors and plays only a minor...
6.
Moller C, Bone W, Cleve A, Klar U, Rotgeri A, Rottmann A, et al.
ChemMedChem
. 2018 Nov;
13(21):2271-2280.
PMID: 30407750
Progesterone plays an important role in the female reproductive system. However, there is also evidence that gynecologic disorders/diseases such as uterine fibroids and endometriosis are progesterone-dependent. Steroidal and non-steroidal selective...
7.
Wagenfeld A, Bone W, Schwede W, Fritsch M, Fischer O, Moeller C
Hum Reprod
. 2013 Jun;
28(8):2253-64.
PMID: 23739217
Study Question: Does the novel progesterone receptor (PR) modulator BAY 1002670, based on its preclinical pharmacological profile, offer a potential novel treatment option for uterine fibroids? Summary Answer: The newly...
8.
Bone W, Walden C, Fritsch M, Voigtmann U, Leifke E, Gottwald U, et al.
Reprod Biol Endocrinol
. 2007 Jan;
5:1.
PMID: 17241468
Background: A major event in the post-meiotic development of male germ cells is the formation of the acrosome. This process can be perturbed in C57BL/6 mice by administration of the...
9.
Aaltonen P, Amory J, Anderson R, Behre H, Bialy G, Blithe D, et al.
J Androl
. 2006 Dec;
28(3):362-3.
PMID: 17192594
No abstract available.