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» Authors » Wiktor Kozminski

Wiktor Kozminski

Explore the profile of Wiktor Kozminski including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 93
Citations 1058
Followers 0
Related Specialties
Molecular Biology
Nuclear Medicine
Chemistry
Top 10 Co-Authors
Anna Zawadzka-Kazimierczuk
Krzysztof Kazimierczuk
Jan Stanek
Szymon Zerko
Robert Konrat
Saurabh Saxena
Igor Zhukov
Michal Nowakowski
Maria Misiak
Leonhard Geist
Published In
J Biomol NMR
J Magn Reson
Biomol NMR Assign
Magn Reson Chem
J Biol Chem
Affiliations
Soon will be listed here.
Recent Articles
1.
Potent Biological Activity of Fluorinated Derivatives of 2-Deoxy-d-Glucose in a Glioblastoma Model
Soltyka-Krajewska M, Ziemniak M, Zawadzka-Kazimierczuk A, Skrzypczyk P, Siwiak-Niedbalska E, Jaskiewicz A, et al.
Biomedicines . 2024 Oct; 12(10). PMID: 39457553
Background: One defining feature of various aggressive cancers, including glioblastoma multiforme (GBM), is glycolysis upregulation, making its inhibition a promising therapeutic approach. One promising compound is 2-deoxy-d-glucose (2-DG), a d-glucose...
2.
Buch.-Ham. ex D.Don Cell Suspension Culture as a New Source of Isosaponarin and 3,7,8-Trimethoxy-9-oxo-9H-xanthen-1-yl 6---D-ribopyranosyl--D-allopyranoside and Their Effect on PC-12 Cell Viability
Czarnomska Z, Markowski M, Nawrocka E, Kozminski W, Bazylko A, Szypula W
Int J Mol Sci . 2024 Aug; 25(16). PMID: 39201264
Some species of the Gentianaceae family are a valuable source of secondary metabolites. However, the phytochemical knowledge of some of these species remains insufficient. Therefore, this work focused on the...
3.
Hydroxysteroid 17-β dehydrogenase 14 (HSD17B14) is an L-fucose dehydrogenase, the initial enzyme of the L-fucose degradation pathway
Witecka A, Kazak V, Kwiatkowski S, Kiersztan A, Jagielski A, Kozminski W, et al.
J Biol Chem . 2024 Jun; 300(8):107501. PMID: 38944119
L-Fucose (6-deoxy-L-galactose), a monosaccharide abundant in glycolipids and glycoproteins produced by mammalian cells, has been extensively studied for its role in intracellular biosynthesis and recycling of GDP-L-fucose for fucosylation. However,...
4.
The assignment of B and H resonances in the post-reaction mixture from the dry synthesis of Li(BH NH BH NH BH )
Nawrocka E, Prus A, Owarzany R, Kozminski W, Kazimierczuk K, Fijalkowski K
Magn Reson Chem . 2022 Sep; 61(1):49-54. PMID: 36082753
We report a detailed NMR and NMR study of as synthesised obtained in a novel dry-synthesis method. A combination of 1D and 2D single- and triple-quantum techniques was used for...
5.
Correction: X-ray wavefunction refinement and comprehensive structural studies on bromo-substituted analogues of 2-deoxy-d-glucose in solid state and solution
Ziemniak M, Pawledzio S, Zawadzka-Kazimierczuk A, Dominiak P, Trzybinski D, Kozminski W, et al.
RSC Adv . 2022 Apr; 12(17):10306. PMID: 35427095
[This corrects the article DOI: 10.1039/D1RA08312K.].
6.
X-ray wavefunction refinement and comprehensive structural studies on bromo-substituted analogues of 2-deoxy-d-glucose in solid state and solution
Ziemniak M, Pawledzio S, Zawadzka-Kazmierczuk A, Dominiak P, Trzybinski D, Kozminski W, et al.
RSC Adv . 2022 Apr; 12(14):8345-8360. PMID: 35424802
The structural studies on two bromo-substituted derivatives of 2-deoxy-d-glucose (2-DG), namely 2-deoxy-2-bromo-d-glucose (2-BG) and 2-deoxy-2-bromo-d-mannose (2-BM) are described. 2-DG itself is an inhibitor of hexokinase, the first enzyme in the...
7.
Mechanism of Atg9 recruitment by Atg11 in the cytoplasm-to-vacuole targeting pathway
Coudevylle N, Banas B, Baumann V, Schuschnig M, Zawadzka-Kazimierczuk A, Kozminski W, et al.
J Biol Chem . 2022 Jan; 298(2):101573. PMID: 35007534
Autophagy is a lysosomal degradation pathway for the removal of damaged and superfluous cytoplasmic material. This is achieved by the sequestration of this cargo material within double-membrane vesicles termed autophagosomes....
8.
Structure, dynamics, and function of SrnR, a transcription factor for nickel-dependent gene expression
Mazzei L, Musiani F, Zerko S, Kozminski W, Cianci M, Beniamino Y, et al.
Metallomics . 2021 Dec; 13(12). PMID: 34850061
Streptomyces griseus, a bacterium producing antibacterial drugs and featuring possible application in phytoremediation, expresses two metal-dependent superoxide dismutase (SOD) enzymes, containing either Fe(II) or Ni(II) in their active site. In...
9.
Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with α-actinin
Sponga A, Arolas J, Schwarz T, Jeffries C, Rodriguez Chamorro A, Kostan J, et al.
Sci Adv . 2021 May; 7(22). PMID: 34049882
In sarcomeres, α-actinin cross-links actin filaments and anchors them to the Z-disk. FATZ (filamin-, α-actinin-, and telethonin-binding protein of the Z-disk) proteins interact with α-actinin and other core Z-disk proteins,...
10.
Experimental and Computational Studies on Structure and Energetic Properties of Halogen Derivatives of 2-Deoxy-D-Glucose
Ziemniak M, Zawadzka-Kazimierczuk A, Pawledzio S, Malinska M, Soltyka M, Trzybinski D, et al.
Int J Mol Sci . 2021 Apr; 22(7). PMID: 33918425
The results of structural studies on a series of halogen-substituted derivatives of 2-deoxy-D-glucose (2-DG) are reported. 2-DG is an inhibitor of glycolysis, a metabolic pathway crucial for cancer cell proliferation...