Wiesje van der Flier
Overview
Explore the profile of Wiesje van der Flier including associated specialties, affiliations and a list of published articles.
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32
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1300
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Recent Articles
1.
Le Borgne J, Gomez L, Heikkinen S, Amin N, Ahmad S, Choi S, et al.
Mol Psychiatry
. 2024 Dec;
PMID: 39633006
Due to methodological reasons, the X-chromosome has not been featured in the major genome-wide association studies on Alzheimer's Disease (AD). To address this and better characterize the genetic landscape of...
2.
Guen Y, Luo G, Ambati A, Damotte V, Jansen I, Yu E, et al.
Proc Natl Acad Sci U S A
. 2023 Aug;
120(36):e2302720120.
PMID: 37643212
Across multiancestry groups, we analyzed Human Leukocyte Antigen (HLA) associations in over 176,000 individuals with Parkinson's disease (PD) and Alzheimer's disease (AD) versus controls. We demonstrate that the two diseases...
3.
Frisoni G, van der Flier W
Lancet Neurol
. 2023 May;
22(7):548-549.
PMID: 37236209
No abstract available.
4.
Luo J, Thomassen J, Bellenguez C, Grenier-Boley B, de Rojas I, Castillo A, et al.
JAMA Netw Open
. 2023 May;
6(5):e2313734.
PMID: 37195665
Importance: An estimated 40% of dementia is potentially preventable by modifying 12 risk factors throughout the life course. However, robust evidence for most of these risk factors is lacking. Effective...
5.
Frisoni G, Altomare D, Ribaldi F, Villain N, Brayne C, Mukadam N, et al.
Lancet Reg Health Eur
. 2023 Mar;
26:100576.
PMID: 36895446
Observational population studies indicate that prevention of dementia and cognitive decline is being accomplished, possibly as an unintended result of better vascular prevention and healthier lifestyles. Population aging in the...
6.
Wolzak K, Vermunt L, Del Campo M, Jorge-Oliva M, van Ziel A, Li K, et al.
Alzheimers Dement
. 2023 Feb;
19(8):3563-3574.
PMID: 36825551
Introduction: Cerebrospinal fluid (CSF) biomarkers for specific cellular disease processes are lacking for tauopathies. In this translational study we aimed to identify CSF biomarkers reflecting early tau pathology-associated unfolded protein...
7.
Inguanzo A, Poulakis K, Mohanty R, Schwarz C, Przybelski S, Diaz-Galvan P, et al.
NPJ Parkinsons Dis
. 2023 Jan;
9(1):5.
PMID: 36670121
Dementia with Lewy bodies (DLB) is a neurodegenerative disorder with a wide heterogeneity of symptoms, which suggests the existence of different subtypes. We used data-driven analysis of magnetic resonance imaging...
8.
van de Beek M, van Unnik A, van Steenoven I, van der Zande J, Barkhof F, Teunissen C, et al.
Int J Geriatr Psychiatry
. 2022 Nov;
37(12).
PMID: 36403133
Background And Objectives: Dementia with Lewy Bodies (DLB) is a heterogeneous disease, with variable signs and symptoms across multiple domains. We aimed to identify associations with rate of change in...
9.
Jansen I, van der Lee S, Gomez-Fonseca D, de Rojas I, Dalmasso M, Grenier-Boley B, et al.
Acta Neuropathol
. 2022 Sep;
144(5):821-842.
PMID: 36066633
Amyloid-beta 42 (Aβ42) and phosphorylated tau (pTau) levels in cerebrospinal fluid (CSF) reflect core features of the pathogenesis of Alzheimer's disease (AD) more directly than clinical diagnosis. Initiated by the...
10.
Hendriks S, Peetoom K, Bakker C, Koopmans R, van der Flier W, Papma J, et al.
Alzheimers Dement
. 2022 Jun;
19(3):831-843.
PMID: 35715891
Introduction: Reliable data on the incidence rates for young-onset dementia (YOD) are lacking, but are necessary for research on disease etiology and to raise awareness among health care professionals. Methods:...