Whitney Hornsby
Overview
Explore the profile of Whitney Hornsby including associated specialties, affiliations and a list of published articles.
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35
Citations
730
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Recent Articles
1.
Smith J, Wong Q, Hornsby W, Conomos M, Heavner B, Kullo I, et al.
ArXiv
. 2025 Feb;
PMID: 39990790
Sharing diverse genomic and other biomedical datasets is critical to advance scientific discoveries and their equitable translation to improve human health. However, data sharing remains challenging in the context of...
2.
Ruan Y, Bhukar R, Patel A, Koyama S, Hull L, Truong B, et al.
medRxiv
. 2025 Jan;
PMID: 39867390
The relatively low representation of admixed populations in both discovery and fine-tuning individual-level datasets limits polygenic risk score (PRS) development and equitable clinical translation for admixed populations. Under the assumption...
3.
Urbut S, Cho S, Paruchuri K, Truong B, Haidermota S, Peloso G, et al.
Circ Genom Precis Med
. 2025 Jan;
18(1):e004681.
PMID: 39851049
Background: Earlier identification of high coronary artery disease (CAD) risk individuals may enable more effective prevention strategies. However, existing 10-year risk frameworks are ineffective at earlier identification. We sought to...
4.
Ravi A, Koyama S, Cho S, Haidermota S, Hornsby W, Ellinor P, et al.
JAMA Cardiol
. 2025 Jan;
PMID: 39813027
Importance: Treatment to lower high levels of low-density lipoprotein cholesterol (LDL-C) reduces incident coronary artery disease (CAD) risk but modestly increases the risk for incident type 2 diabetes (T2D). The...
5.
Paruchuri K, Bernardo R, Haidermota S, Lannery K, Finneran P, Wong M, et al.
J Card Fail
. 2025 Jan;
PMID: 39743038
No abstract available.
6.
Schuermans A, Pournamdari A, Lee J, Bhukar R, Ganesh S, Darosa N, et al.
Nat Cardiovasc Res
. 2024 Nov;
3(12):1516-1530.
PMID: 39572695
Cardiac diseases represent common highly morbid conditions for which molecular mechanisms remain incompletely understood. Here we report the analysis of 1,459 protein measurements in 44,313 UK Biobank participants to characterize...
7.
Urbut S, Ding Y, Jiang X, Hornsby W, Gusev A, Natarajan P, et al.
medRxiv
. 2024 Nov;
PMID: 39568791
Early identification of high-risk individuals through the analysis of their unique disease trajectories has a strong potential to support efficient prevention and clinical management across a range of chronic conditions....
8.
Yu Z, Vromman A, Nguyen N, Schuermans A, Rentz T, Vellarikkal S, et al.
bioRxiv
. 2024 Nov;
PMID: 39554199
Plasma proteomic profiles associated with subclinical somatic mutations in blood cells may offer novel insights into downstream clinical consequences. Here, we explore such patterns in clonal hematopoiesis of indeterminate potential...
9.
Koyama S, Yu Z, Choi S, Jurgens S, Selvaraj M, Klarin D, et al.
medRxiv
. 2024 Oct;
PMID: 39371182
Rare coding alleles play crucial roles in the molecular diagnosis of genetic diseases. However, the systemic identification of these alleles has been challenging due to their scarcity in the general...
10.
Cho S, Rivera R, Koyama S, Kim M, Ganesh S, Bhattacharya R, et al.
JACC Adv
. 2024 Sep;
3(10):101257.
PMID: 39290815
Background: Atherosclerotic cardiovascular disease (ASCVD) risk estimation based on the pooled cohort equation (PCE) overestimates in population-based cohorts. Whether it performs equally across disaggregated demographics in health care populations is...