Md Mesbah Uddin
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Explore the profile of Md Mesbah Uddin including associated specialties, affiliations and a list of published articles.
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946
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Recent Articles
1.
Pershad Y, Uddin M, Xue L, Haessler J, Collins J, Mack T, et al.
medRxiv
. 2025 Jan;
PMID: 39867366
Clonal hematopoiesis of indeterminate potential (CHIP) is associated with increased mortality and malignancy risk, yet the determinants of clonal expansion remain poorly understood. We performed sequencing at >4,000x depth of...
2.
Supriami K, Urbut S, Tello-Ayala J, Unlu O, Friedman S, Abou-Karam R, et al.
JAMA Netw Open
. 2025 Jan;
8(1):e2455368.
PMID: 39836422
Importance: Disease characteristics of genetically mediated coronary artery disease (CAD) on coronary angiography and the association of genomic risk with outcomes after coronary angiography are not well understood. Objective: To...
3.
Yu Z, Vromman A, Nguyen N, Schuermans A, Rentz T, Vellarikkal S, et al.
bioRxiv
. 2024 Nov;
PMID: 39554199
Plasma proteomic profiles associated with subclinical somatic mutations in blood cells may offer novel insights into downstream clinical consequences. Here, we explore such patterns in clonal hematopoiesis of indeterminate potential...
4.
Uddin M, Saadatagah S, Niroula A, Yu B, Hornsby W, Ganesh S, et al.
Nat Commun
. 2024 Sep;
15(1):7858.
PMID: 39251642
Clonal hematopoiesis of indeterminate potential (CHIP) is linked to diverse aging-related diseases, including hematologic malignancy and atherosclerotic cardiovascular disease (ASCVD). While CHIP is common among older adults, the underlying factors...
5.
Zuriaga M, Yu Z, Matesanz N, Truong B, Ramos-Neble B, Asensio-Lopez M, et al.
Eur Heart J
. 2024 Aug;
45(43):4601-4615.
PMID: 39212933
Background And Aims: Somatic mutations in the TET2 gene that lead to clonal haematopoiesis (CH) are associated with accelerated atherosclerosis development in mice and a higher risk of atherosclerotic disease...
6.
Xiao C, Kurella Tamura M, Pan Y, Rao V, Missikpode C, Vlasschaert C, et al.
Alzheimers Dement
. 2024 Aug;
20(10):6960-6971.
PMID: 39115897
Introduction: Clonal hematopoiesis of indeterminate potential (CHIP) and dementia disproportionately burden patients with chronic kidney disease (CKD). The association between CHIP and cognitive impairment in CKD patients is unknown. Methods:...
7.
Zon R, Sekar A, Clapham K, Oren O, Niroula A, Bick A, et al.
Blood
. 2024 Aug;
144(20):2149-2154.
PMID: 39102652
Venous thromboembolism (VTE) is common among older individuals, but provoking factors are not identified in many cases. Patients with myeloid malignancies, especially myeloproliferative neoplasms (MPNs), are at increased risk for...
8.
Levy D, Kirmani S, Huan T, Van Amburg J, Joehanes R, Uddin M, et al.
Res Sq
. 2024 Jul;
PMID: 39070619
With age, hematopoietic stem cells can acquire somatic mutations in leukemogenic genes that confer a proliferative advantage in a phenomenon termed "clonal hematopoiesis of indeterminate potential" (CHIP). How these mutations...
9.
Vlasschaert C, Pan Y, Chen J, Akwo E, Rao V, Hixson J, et al.
medRxiv
. 2024 Jul;
PMID: 38946975
Background: Clonal hematopoiesis of indeterminate potential (CHIP) is a common inflammatory condition of aging that causes myriad end-organ damage. We have recently shown associations for CHIP with acute kidney injury...
10.
Gilliland T, Dron J, Selvaraj M, Trinder M, Paruchuri K, Urbut S, et al.
Circ Res
. 2024 Jun;
135(2):265-276.
PMID: 38828614
Background: Dyslipoproteinemia often involves simultaneous derangements of multiple lipid traits. We aimed to evaluate the phenotypic and genetic characteristics of combined lipid disturbances in a general population-based cohort. Methods: Among...