Wenbin Xie
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Explore the profile of Wenbin Xie including associated specialties, affiliations and a list of published articles.
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20
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19
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Recent Articles
1.
Geng Z, Wang Y, Ma M, Wei Y, Xie W, Cheng J, et al.
Eur J Med Chem
. 2025 Feb;
289:117428.
PMID: 40010272
Multidrug Resistance (MDR) is an essential cause of failure of tumor chemotherapy, and P-glycoprotein (P-gp) overexpression is one of the major causes of MDR in tumor cells. Hederagenin (HRG) derivatives...
2.
Shi Q, Ni A, Li K, Su W, Xie W, Zheng H, et al.
Alzheimers Dement
. 2025 Feb;
21(2):e14593.
PMID: 39988572
Introduction: Foundational models suggest Alzheimer's disease (AD) can be diagnosed using retinal images, but the specific structural features remain poorly understood. This study investigates retinal vascular changes in individuals with...
3.
Yang Y, Yu Q, Zhang H, Liu Y, Wang H, Yang N, et al.
J Control Release
. 2025 Feb;
380:256-268.
PMID: 39894265
Tumor-specific T cells play a crucial role in tumor immunity. However, these cells are often scarce and functionally exhausted within the tumor microenvironment (TME), leading to the limited efficacy of...
4.
Xie W, Li H, Yu T, Zhu Y, Gao J, Yang X, et al.
J Med Chem
. 2025 Jan;
68(3):2694-2719.
PMID: 39817810
Sepsis is a systemic inflammatory response caused by infection and is a leading cause of death worldwide. We designed and synthesized a series of hederagenin analogues with anti-inflammatory activity. The...
5.
He S, Ye X, Xie W, Shen Y, Yang S, Zhong X, et al.
Sci Data
. 2024 Nov;
11(1):1251.
PMID: 39567563
Ultrawidefield fundus (UWF) images have a wide imaging range (200° of the retinal region), which offers the opportunity to show more information for ophthalmic diseases. Image quality assessment (IQA) is...
6.
Zhang W, Shi X, Huang S, Yu Q, Wu Z, Xie W, et al.
Cancer Immunol Immunother
. 2024 Oct;
73(12):245.
PMID: 39358493
Neoantigen vaccines represent an emerging and promising strategy in the field of tumor immunotherapy. Despite their potential, designing an effective neoantigen vaccine remains a challenge due to the current limitations...
7.
Jiang C, Xie W, Zheng J, Yan B, Luo J, Zhang J
Biosensors (Basel)
. 2024 Aug;
14(8).
PMID: 39194635
Over the past decades, feature-based statistical machine learning and deep neural networks have been extensively utilized for automatic sleep stage classification (ASSC). Feature-based approaches offer clear insights into sleep characteristics...
8.
Li Z, Liu T, Xie W, Wang Z, Gong B, Yang M, et al.
Eur J Pharmacol
. 2024 Aug;
983:176901.
PMID: 39181225
Constant efforts have been made to move towards maintaining the positive anti-inflammatory functions of glucocorticoids (GCs) while minimizing side effects. The anti-inflammatory effect of GCs is mainly attributed to the...
9.
Yu Q, Zhang T, He T, Yang Y, Zhang W, Kang Y, et al.
Immunology
. 2024 Aug;
173(4):654-671.
PMID: 39174487
Personalized neoantigen therapy has shown long-term and stable efficacy in specific patient populations. However, not all patients have sufficient levels of neoantigens for treatment. Although somatic mutations are commonly found...
10.
Ye X, He S, Dan R, Yang S, Xv J, Lu Y, et al.
Ophthalmol Ther
. 2024 Aug;
13(10):2645-2659.
PMID: 39127983
Introduction: The aim of this work is to develop a deep learning (DL) system for rapidly and accurately screening for intraocular tumor (IOT), retinal detachment (RD), vitreous hemorrhage (VH), and...