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Wen-Lu Zhang

Explore the profile of Wen-Lu Zhang including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 191
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Recent Articles
11.
Ren F, Yang X, Hu Z, Wong V, Xu H, Ren J, et al.
EBioMedicine . 2019 Nov; 49:232-246. PMID: 31680002
Background: Hepatitis B surface antigen (HBsAg) is one of the important clinical indexes for hepatitis B virus (HBV) infection diagnosis and sustained seroconversion of HBsAg is an indicator for functional...
12.
Li W, Zhou H, Chen Y, Cai X, Tang H, Ren J, et al.
Cancer Lett . 2019 Mar; 451:156-167. PMID: 30867140
NAD(P)H: quinone oxidoreductase 1 (NQO1) is an antioxidant enzyme which is associated with poor prognosis in human breast, colon, lung and liver cancers. However, the molecular mechanisms underlying the pro-tumorigenic...
13.
Wei X, Gan C, Cui J, Luo Y, Cai X, Yuan Y, et al.
Antimicrob Agents Chemother . 2018 Sep; 62(12). PMID: 30224531
The capsid of the hepatitis B virus is an attractive antiviral target for developing therapies against chronic hepatitis B infection. Currently available core protein allosteric modulators (CpAMs) mainly affect one...
14.
Ren J, Hu J, Cheng S, Yu H, Wong V, Law B, et al.
Hepatology . 2018 Apr; 68(4):1260-1276. PMID: 29624717
Conclusion: SIRT3 is a host factor epigenetically restricting HBV cccDNA transcription by acting cooperatively with histone methyltransferase; these data provide a rationale for the use of SIRT3 activators in the...
15.
Chen J, Gan C, Cai X, Zhang W, Long Q, Wei X, et al.
J Virol Methods . 2018 Feb; 255:52-59. PMID: 29447911
Fusion core proteins of Hepatitis B virus can be used to study core protein functions or capsid trafficking. A problem in constructing fusion core proteins is functional impairment of the...
16.
Liu Y, Luo Y, Cai X, Long Q, Gan C, Yang L, et al.
Virol Sin . 2017 Mar; 32(2):167-170. PMID: 28353186
No abstract available.
17.
Tao N, Zhou H, Tang H, Cai X, Zhang W, Ren J, et al.
Oncotarget . 2016 Jul; 7(31):50117-50130. PMID: 27367026
SIRT3, a class III histone deacetylase, has been implicated in various cancers as a novel therapeutic target. In hepatocellular carcinoma (HCC), we previously reported that SIRT3 induced cell apoptosis by...
18.
Luo Y, Tao Y, Cai X, Zhang W, Long Q, Guo H, et al.
Antiviral Res . 2016 Jan; 126:99-107. PMID: 26738784
Nucleos(t)ide analogues (NUCs) susceptibility assay is important for the study of hepatitis B virus (HBV) drug resistance. The purpose of susceptibility assay is to test the sensitivity of a specific...
19.
Xiang M, Cai X, Zhang W, Huang A, Hu J
Zhongguo Yi Xue Ke Xue Yuan Xue Bao . 2013 Mar; 35(1):13-8. PMID: 23469784
Objective: To establish a stable cell line that can replicate hepatitis B virus (HBV) DNA carrying the reverse transcriptase sequence derived from a clinical isolate. Methods: Nested PCR was used...
20.
Hu J, Xu G, Lei L, Zhang W, Hu Y, Huang A, et al.
Z Naturforsch C J Biosci . 2012 Aug; 67(5-6):327-30. PMID: 22888539
Translation elongation factor 1A (eEF1A) is a factor critically involved in the process of protein synthesis. The activity of eEF1A has been shown by several studies to be regulated by...