Wen-Hsien Liu
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Explore the profile of Wen-Hsien Liu including associated specialties, affiliations and a list of published articles.
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28
Citations
495
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Recent Articles
11.
Wu J, Yang K, Cai S, Zhang X, Hu L, Lin F, et al.
Nat Commun
. 2022 Nov;
13(1):7321.
PMID: 36443297
Plasma cells (PC) are antibody-secreting cells and terminal effectors in humoral responses. PCs differentiate directly from activated B cells in response to T cell-independent (TI) antigens or from germinal center...
12.
Yang C, Liu Y, Hu Y, Fang L, Huang Z, Cui H, et al.
Cell Mol Immunol
. 2022 Aug;
19(9):1030-1041.
PMID: 35962189
Aberrant expression of Myc is one of the most common oncogenic events in human cancers. Scores of Myc inhibitors are currently under development for treating Myc-driven cancers. In addition to...
13.
Liu Q, Zhou Y, Ma L, Gu F, Liao K, Liu Y, et al.
Carbohydr Polym
. 2022 Apr;
288:119377.
PMID: 35450639
Seaweeds are important "blue food" and some seaweeds have been demonstrated that have the immunoregulation activities and benefit for human health. However, which immune cell subsets are targeted and how...
14.
Zhai X, Liu K, Fang H, Zhang Q, Gao X, Liu F, et al.
Sci Adv
. 2021 Dec;
7(49):eabk0490.
PMID: 34860557
Early-activated CD8 T cells increase both aerobic glycolysis and mitochondrial oxidative phosphorylation (OXPHOS). However, whether and how the augmentation of OXPHOS regulates differentiation of effector CD8 T cell remains unclear....
15.
Liu C, Ma L, Wang Y, Zhao J, Chen P, Chen X, et al.
Sci Adv
. 2021 Oct;
7(41):eabg6262.
PMID: 34623920
Molecular pathways controlling emigration of mature thymocytes from thymus to the periphery remain incompletely understood. Here, we show that T cell–specific ablation of glycogen synthase kinase 3 (GSK3) led to...
16.
Yang L, Chen W, Li L, Xiao Y, Fan S, Zhang Q, et al.
Front Immunol
. 2021 Sep;
12:722273.
PMID: 34526995
Follicular helper T (T) cells are specialized CD4 helper T cells that provide help to B cells in humoral immunity. However, the molecular mechanism underlying generation of T cells is...
17.
Zhou X, Ma F, Xie J, Yuan M, Li Y, Shaabani N, et al.
Cell Rep
. 2021 May;
35(6):109109.
PMID: 33932326
It is unclear whether individuals with enormous diversity in B cell receptor repertoires are consistently able to mount effective antibody responses against SARS-CoV-2. We analyzed antibody responses in a cohort...
18.
Huang J, Cai C, Zheng T, Wu X, Wang D, Zhang K, et al.
Arterioscler Thromb Vasc Biol
. 2020 Apr;
40(7):1705-1721.
PMID: 32268790
Objective: A decrease in nitric oxide, leading to vascular smooth muscle cell proliferation, is a common pathological feature of vascular proliferative diseases. Nitric oxide synthesis by eNOS (endothelial nitric oxide...
19.
Zheng S, Li H, Lai K, Chen M, Fu G, Liu W, et al.
J Biophotonics
. 2018 Apr;
11(9):e201800073.
PMID: 29701012
The migration of immune cells is crucial to the immune response. Visualization of these processes has previously been limited because of the imaging depth. We developed a deep-penetrating, sensitive and...
20.
Jin H, Oda H, Chen P, Yang C, Zhou X, Kang S, et al.
PLoS Genet
. 2017 Feb;
13(2):e1006623.
PMID: 28241004
MicroRNAs (miRNAs) are thought to exert their functions by modulating the expression of hundreds of target genes and each to a small degree, but it remains unclear how small changes...