Wen-Chi Hsueh
Overview
Explore the profile of Wen-Chi Hsueh including associated specialties, affiliations and a list of published articles.
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Articles
59
Citations
2354
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Recent Articles
1.
Ramirez-Luzuriaga M, Kobes S, Hsueh W, Baier L, Hanson R
Hum Mol Genet
. 2024 Mar;
33(11):981-990.
PMID: 38483351
Most genetic variants associated with adult height have been identified through large genome-wide association studies (GWASs) in European-ancestry cohorts. However, it is unclear how these variants influence linear growth during...
2.
Wedekind L, Mahajan A, Hsueh W, Chen P, Olaiya M, Kobes S, et al.
Diabetologia
. 2023 Mar;
66(5):847-860.
PMID: 36862161
Aims/hypothesis: There is limited information on how polygenic scores (PSs), based on variants from genome-wide association studies (GWASs) of type 2 diabetes, add to clinical variables in predicting type 2...
3.
Bandesh K, Traurig M, Chen P, Hsueh W, Hanson R, Piaggi P, et al.
Int J Obes (Lond)
. 2023 Feb;
47(6):434-442.
PMID: 36806387
Background: Genome-wide association studies have shown that body mass index (BMI), an estimate of obesity, is highly polygenic. Individual variants typically have small effect sizes, making it challenging to identify...
4.
Morales L, Cromack D, Tripathy D, Fourcaudot M, Kumar S, Curran J, et al.
Sci Rep
. 2021 Jan;
11(1):1932.
PMID: 33479282
Insulin is an essential hormone that regulates glucose homeostasis and metabolism. Insulin resistance (IR) arises when tissues fail to respond to insulin, and it leads to serious health problems including...
5.
Hanson R, Van Hout C, Hsueh W, Shuldiner A, Kobes S, Sinha M, et al.
Diabetologia
. 2020 Sep;
63(12):2616-2627.
PMID: 32886191
Aims/hypothesis: Prevalence of type 2 diabetes differs among human ancestry groups, and many hypotheses invoke differential natural selection to account for these differences. We sought to assess the potential role...
6.
Piaggi P, Koroglu C, Nair A, Sutherland J, Muller Y, Kumar P, et al.
J Clin Endocrinol Metab
. 2020 Aug;
105(11).
PMID: 32818236
Background: Obesity and energy expenditure (EE) are heritable and genetic variants influencing EE may contribute to the development of obesity. We sought to identify genetic variants that affect EE in...
7.
Kim H, Ye B, Gosalia N, Koroglu C, Hanson R, Hsueh W, et al.
Am J Hum Genet
. 2020 Jul;
107(2):251-264.
PMID: 32640185
Applying exome sequencing to populations with unique genetic architecture has the potential to reveal novel genes and variants associated with traits and diseases. We sequenced and analyzed the exomes of...
8.
Muller Y, Hanson R, Mahkee D, Piaggi P, Kobes S, Hsueh W, et al.
Obesity (Silver Spring)
. 2020 Feb;
28(3):676-682.
PMID: 32030914
Objective: Insulinlike growth factor II (IGF-II) regulates metabolism and growth. In humans, both positive and negative relationships have been reported between serum IGF-II levels and obesity. This study assessed the...
9.
Hanson R, Safabakhsh S, Curtis J, Hsueh W, Jones L, Aflague T, et al.
Diabetologia
. 2019 Jul;
62(9):1647-1652.
PMID: 31280340
Aims/hypothesis: Variants in CREBRF (rs12513649 and rs373863828) have been strongly associated with increased BMI and decreased risk of type 2 diabetes in Polynesian populations; the A allele at rs373863828 is...
10.
Muller Y, Hanson R, Piaggi P, Chen P, Wiessner G, Okani C, et al.
Obesity (Silver Spring)
. 2019 Mar;
27(5):845-854.
PMID: 30887699
Objective: Meta-analyses of genome-wide association studies in Europeans have identified > 98 loci for BMI. Transferability of these established associations in Pima Indians was analyzed. Methods: Among 98 lead single...