Braxton D Mitchell
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Explore the profile of Braxton D Mitchell including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Nguyen K, Xu H, Gaynor B, McArdle P, OConnor T, Perry J, et al.
Stroke
. 2025 Feb;
56(3):640-648.
PMID: 39993026
Background: Stroke incidence is decreasing in older ages but increasing in young adults. These divergent trends are at least partially attributable not only to diverging trends in stroke risk factors...
2.
Iyer K, Clarke S, Guarischi-Sousa R, Gjoni K, Heath A, Young E, et al.
J Am Heart Assoc
. 2025 Feb;
14(4):e036499.
PMID: 39950338
Background: Genome-wide association studies have identified several hundred susceptibility single nucleotide variants for coronary artery disease (CAD). Despite single nucleotide variant-based genome-wide association studies improving our understanding of the genetics...
3.
Li X, Chen H, Selvaraj M, Van Buren E, Zhou H, Wang Y, et al.
Nat Comput Sci
. 2025 Feb;
5(2):125-143.
PMID: 39920506
Large-scale whole-genome sequencing (WGS) studies have improved our understanding of the contributions of coding and noncoding rare variants to complex human traits. Leveraging association effect sizes across multiple traits in...
4.
Jakubek Y, Ma X, Stilp A, Yu F, Bacon J, Wong J, et al.
Am J Hum Genet
. 2025 Jan;
112(2):276-290.
PMID: 39809269
Mosaic loss of Y (mLOY) is the most common somatic chromosomal alteration detected in human blood. The presence of mLOY is associated with altered blood cell counts and increased risk...
5.
Feng L, Ye Z, Pan Y, McCoy R, Mitchell B, Kochunov P, et al.
medRxiv
. 2024 Dec;
PMID: 39677426
Importance: The American Heart Association introduced Life's Essential 8 (LE8) as a checklist of healthy lifestyle factors to help older individuals maintain and improve cardiovascular health and live longer. How...
6.
Donohue B, Gao S, Nichols T, Adhikari B, Ma Y, Jahanshad N, et al.
Hum Brain Mapp
. 2024 Nov;
45(17):e70044.
PMID: 39593222
National and international biobanking efforts led to the collection of large and inclusive imaging genetics datasets that enable examination of the contribution of genetic and environmental factors to human brains...
7.
Lewis J, Ryan K, Streeten E, Whitlatch H, Daue M, Tanner K, et al.
Clin Transl Sci
. 2024 Nov;
17(11):e70079.
PMID: 39576732
Antiplatelet therapy with a P2Y receptor inhibitor, in combination with aspirin, is standard of care for medical management of patients with coronary artery disease, and flexibility in prescribing options among...
8.
9.
Deng A, Xu H, Gaynor B, Cole J, Giese A, Schirmer M, et al.
J Stroke Cerebrovasc Dis
. 2024 Nov;
34(1):108109.
PMID: 39489406
Background: The sulfonylurea receptor 1 (SUR1) is a known mediator of cerebral edema in large ischemic strokes, however, genetically induced response variability has yet to be evaluated. SUR1, encoded by...
10.
Rocheleau G, Clarke S, Auguste G, Hasbani N, Morrison A, Heath A, et al.
Nat Commun
. 2024 Oct;
15(1):8741.
PMID: 39384761
Whole genome sequences (WGS) enable discovery of rare variants which may contribute to missing heritability of coronary artery disease (CAD). To measure their contribution, we apply the GREML-LDMS-I approach to...