Weiling He
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Explore the profile of Weiling He including associated specialties, affiliations and a list of published articles.
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80
Citations
1799
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Recent Articles
1.
He W, Huang F, Wu X, Xie A, Sun W, Liu P, et al.
BMC Med Imaging
. 2025 Mar;
25(1):73.
PMID: 40038586
Objectives: To explore the feasibility of a one-beat protocol and ultra-low tube voltage of 60 kVp in coronary CT angiography (CCTA). Methods: This prospective study enrolled 107 patients (body mass...
2.
Li K, Yu X, Xu Y, Wang H, Liu Z, Wu C, et al.
Nat Commun
. 2025 Feb;
16(1):1629.
PMID: 39952937
Non-nucleotide stimulators of interferon gene (STING) agonists hold promise as immunotherapeutic agents for postsurgical adjuvant treatment of tumors. However, their limited effect duration hampers therapeutic effectiveness, necessitating prolonged administration of...
3.
Wang Y, Qiu X, Li Q, Qin J, Ye L, Zhang X, et al.
J Transl Med
. 2025 Feb;
23(1):175.
PMID: 39934919
Background: Colorectal cancer (CRC) presents significant treatment challenges due to its high heterogeneity and complex intercellular interactions. Further exploration of CRC subtypes and interactions among tumor-specific clusters will facilitate the...
4.
Huang X, Wei R, Li Q, Qiu X, Li P, He W
Int J Surg
. 2025 Feb;
PMID: 39903566
The natural orifice specimen extraction surgery (NOSES) procedure is an innovative approach to treating colorectal cancer that offers several advantages. First, the NOSES technique is minimally invasive, reducing the incidence...
5.
Song S, Qiu X, Huang S, Tian H, Pu R, Huang J, et al.
ACS Appl Mater Interfaces
. 2025 Jan;
17(6):9074-9086.
PMID: 39874587
The clinical application of tyrosine kinase inhibitors (TKIs) is rapidly growing and has emerged as a cornerstone in the treatment of both solid tumors and hematologic malignancies. However, resistance to...
6.
Liu C, Liang H, Wan A, Xiao M, Sun L, Yu Y, et al.
Nat Commun
. 2025 Jan;
16(1):798.
PMID: 39824841
Epitranscriptomic modifications, particularly N6-methyladenosine (mA), are crucial regulators of gene expression, influencing processes such as RNA stability, splicing, and translation. Traditional computational methods for detecting mA from Nanopore direct RNA...
7.
Wang Z, Di Y, Wen X, Liu Y, Ye L, Zhang X, et al.
Sci Transl Med
. 2024 Nov;
16(774):eado8333.
PMID: 39565874
5-Fluorouracil (5-FU) chemoresistance contributes to poor therapeutic response and prognosis of gastric cancer (GC), for which effective strategies to overcome chemoresistance are limited. Here, using a CRISPR-Cas9 system, we identified...
8.
Wu C, Liu X, Liu R, Song S, Zheng Z, Zeng Y, et al.
Adv Sci (Weinh)
. 2024 Nov;
12(2):e2407239.
PMID: 39560161
The epidermal growth factor receptor (EGFR) is a validated therapeutic target for RAS/RAF wild-type colorectal cancer (CRC). However, monoclonal antibody-based anti-EGFR therapies such as cetuximab have limited effectiveness. Herein, it...
9.
Di Y, Wang Z, Xiao J, Zhang X, Ye L, Wen X, et al.
Sci Adv
. 2024 Sep;
10(38):eadp0719.
PMID: 39292786
Aberrant activation of IL-18 signaling regulates tumor immune evasion and progression. However, the underlying mechanism remains unclear. Here, we report that long-chain acyl-CoA synthase 6 (ACSL6) is highly expressed in...
10.
Song M, Huang S, Wu X, Zhao Z, Liu X, Wu C, et al.
Redox Biol
. 2024 Sep;
76:103349.
PMID: 39260061
Chemoresistance remains a principal culprit for the treatment failure in colorectal cancer (CRC), especially for patients with recurrent or metastatic disease. Deciphering the molecular basis of chemoresistance may lead to...