Weichuan Yu
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Explore the profile of Weichuan Yu including associated specialties, affiliations and a list of published articles.
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76
Citations
921
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Recent Articles
11.
Zhou C, Dai S, Lin Y, Lian S, Fan X, Li N, et al.
J Proteome Res
. 2022 Dec;
22(1):101-113.
PMID: 36480279
Improving the sensitivity of protein-protein interaction detection and protein structure probing is a principal challenge in cross-linking mass spectrometry (XL-MS) data analysis. In this paper, we propose an exhaustive cross-linking...
12.
He W, Tang H, Li J, Hou C, Shen X, Li C, et al.
Neurosci Bull
. 2022 May;
38(9):1057-1068.
PMID: 35639276
In animal experiments, ischemic stroke is usually induced through middle cerebral artery occlusion (MCAO), and quality assessment of this procedure is crucial. However, an accurate assessment method based on 18F-fluorodeoxyglucose...
13.
Hu T, Li J, Long M, Wu J, Zhang Z, Xie F, et al.
Front Cell Dev Biol
. 2022 May;
10:854640.
PMID: 35493102
Structural variations (SVs) are common genetic alterations in the human genome that could cause different phenotypes and diseases, including cancer. However, the detection of structural variations using the second-generation sequencing...
14.
Moradi A, Dai S, Wong E, Zhu G, Yu F, Lam H, et al.
Biomolecules
. 2021 Aug;
11(8).
PMID: 34439883
Isotopically dimethyl labeling was applied in a quantitative post-translational modification (PTM) proteomic study of phosphoproteomic changes in the drought responses of two contrasting soybean cultivars. A total of 9457 phosphopeptides...
15.
Tam C, Lim C, Luk A, Ng A, Lee H, Jiang G, et al.
Genome Med
. 2021 Feb;
13(1):29.
PMID: 33608049
Background: The clinical utility of personal genomic information in identifying individuals at increased risks for dyslipidemia and cardiovascular diseases remains unclear. Methods: We used data from Biobank Japan (n = ...
16.
Dai J, Yu F, Zhou C, Yu W
IEEE/ACM Trans Comput Biol Bioinform
. 2020 May;
18(6):2884-2890.
PMID: 32356758
Peptide identification from tandem mass spectrometry data is a fundamental task in computational proteomics. Traditional algorithms perform well when facing unmodified peptides. However, when peptides have post-translational modifications (PTMs), these...
17.
Zhang S, Jiang W, Ma R, Yu W
BMC Med Genomics
. 2020 Jan;
12(Suppl 7):133.
PMID: 31888606
Background: In genome-wide association study (GWAS), conventional interaction detection methods such as BOOST are mostly based on SNP-SNP interactions. Although single nucleotides are the building blocks of human genome, single...
18.
Gao Y, Chuai G, Yu W, Qu S, Liu Q
Brief Bioinform
. 2019 Jul;
21(4):1448-1454.
PMID: 31267129
For genome-wide CRISPR off-target cleavage sites (OTS) prediction, an important issue is data imbalance-the number of true OTS recognized by whole-genome off-target detection techniques is much smaller than that of...
19.
Dai J, Jiang W, Yu F, Yu W
Bioinformatics
. 2019 Jan;
35(2):251-257.
PMID: 30649350
Motivation: Cross-linking technique coupled with mass spectrometry (MS) is widely used in the analysis of protein structures and protein-protein interactions. In order to identify cross-linked peptides from MS data, we...
20.
Liu S, Yu F, Hu Q, Wang T, Yu L, Du S, et al.
J Proteome Res
. 2018 Aug;
17(9):3195-3213.
PMID: 30084631
An in planta chemical cross-linking-based quantitative interactomics (IPQCX-MS) workflow has been developed to investigate in vivo protein-protein interactions and alteration in protein structures in a model organism, Arabidopsis thaliana. A...