Webster K Cavenee
Overview
Explore the profile of Webster K Cavenee including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
142
Citations
22685
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Bhoopathi P, Mannangatti P, Pradhan A, Kumar A, Maji S, Lang F, et al.
J Cell Physiol
. 2024 May;
239(8):e31302.
PMID: 38775127
Primary, glioblastoma, and secondary brain tumors, from metastases outside the brain, are among the most aggressive and therapeutically resistant cancers. A physiological barrier protecting the brain, the blood-brain barrier (BBB),...
2.
Harachi M, Masui K, Shimizu E, Murakami K, Onizuka H, Muragaki Y, et al.
Acta Neuropathol Commun
. 2024 Mar;
12(1):40.
PMID: 38481314
DNA methylation is crucial for chromatin structure and gene expression and its aberrancies, including the global "hypomethylator phenotype", are associated with cancer. Here we show that an underlying mechanism for...
3.
Maji S, Pradhan A, Kumar A, Bhoopathi P, Mannangatti P, Guo C, et al.
Proc Natl Acad Sci U S A
. 2023 Nov;
120(45):e2307094120.
PMID: 37922327
Bone metastasis is a frequent and incurable consequence of advanced prostate cancer (PC). An interplay between disseminated tumor cells and heterogeneous bone resident cells in the metastatic niche initiates this...
4.
Lauer R, Barry M, Smith T, Thomas A, Wu J, Du R, et al.
Elife
. 2023 Jan;
12.
PMID: 36645410
Background: We have previously shown that the long non-coding (lnc)RNA (; formerly ) functions as a trans-dominant negative oncogene by targeting the previously unrecognized prostate cancer suppressor gene (a homolog...
5.
Zhao X, Cohen E, William Jr W, Bianchi J, Abraham J, Magee D, et al.
Proc Natl Acad Sci U S A
. 2022 Nov;
119(47):e2213835119.
PMID: 36395141
Somatic copy number alterations (SCNAs), generally (1) losses containing interferons and interferon-pathway genes, many on chromosome 9p, predict immune-cold, immune checkpoint therapy (ICT)-resistant tumors (2); however, genomic regions mediating these...
6.
Masui K, Cavenee W, Mischel P, Shibata N
Cancer Sci
. 2022 Mar;
113(5):1555-1563.
PMID: 35271755
Cancer cells depend on metabolic reprogramming for survival, undergoing profound shifts in nutrient sensing, nutrient uptake and flux through anabolic pathways, in order to drive nucleotide, lipid, and protein synthesis...
7.
Modi J, Roy A, Pradhan A, Kumar A, Talukdar S, Bhoopathi P, et al.
Int J Mol Sci
. 2022 Jan;
23(1).
PMID: 35008495
Melanoma differentiation associated gene-7/interleukin-24 (MDA-7/IL-24), a secreted protein of the IL-10 family, was first identified more than two decades ago as a novel gene differentially expressed in terminally differentiating human...
8.
Pradhan A, Maji S, Bhoopathi P, Talukdar S, Mannangatti P, Guo C, et al.
Proc Natl Acad Sci U S A
. 2021 May;
118(21).
PMID: 34016751
Melanoma differentiation associated gene-9 (MDA-9), Syntenin-1, or syndecan binding protein is a differentially regulated prometastatic gene with elevated expression in advanced stages of melanoma. MDA-9/Syntenin expression positively associates with advanced...
9.
Harachi M, Masui K, Cavenee W, Mischel P, Shibata N
Metabolites
. 2021 Apr;
11(4).
PMID: 33916219
Metabolic reprogramming is an emerging hallmark of cancer and is driven by abnormalities of oncogenes and tumor suppressors. Accelerated metabolism causes cancer cell aggression through the dysregulation of rate-limiting metabolic...
10.
Anaya D, Dogra P, Wang Z, Haider M, Ehab J, Jeong D, et al.
Cancers (Basel)
. 2021 Jan;
13(3).
PMID: 33503971
Chemotherapy remains a primary treatment for metastatic cancer, with tumor response being the benchmark outcome marker. However, therapeutic response in cancer is unpredictable due to heterogeneity in drug delivery from...