Walter G Thomas
Overview
Explore the profile of Walter G Thomas including associated specialties, affiliations and a list of published articles.
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Articles
88
Citations
2877
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Recent Articles
1.
Redd M, Yoshikawa Y, Khan N, Waqar M, Saez N, Outhwaite J, et al.
Eur Heart J
. 2023 Dec;
45(17):1571-1574.
PMID: 38095341
No abstract available.
2.
Bloxham C, Hulme K, Fierro F, Fercher C, Pegg C, OBrien S, et al.
Biochem Pharmacol
. 2023 Nov;
219:115932.
PMID: 37989413
Bitter taste receptors (T2R) are a subfamily of G protein-coupled receptors that enable humans to detect aversive and toxic substances. The ability to discern bitter compounds varies between individuals and...
3.
Ashton K, Kiessling C, Thompson J, Aziz A, Thomas W, Headrick J, et al.
Exp Gerontol
. 2022 Nov;
171:112011.
PMID: 36347360
Phenotypic and transcriptomic evidence of early cardiac aging, and associated mechanisms, were investigated in young to middle-aged male mice (C57Bl/6; ages 8, 16, 32, 48 wks). Left ventricular gene expression...
4.
Eagles D, Saez N, Krishnarjuna B, Bradford J, Chin Y, Starobova H, et al.
Proc Natl Acad Sci U S A
. 2022 Feb;
119(7).
PMID: 35131940
Venoms are excellent model systems for studying evolutionary processes associated with predator-prey interactions. Here, we present the discovery of a peptide toxin, MIITX-Mg1a, which is a major component of the...
5.
Mohamed R, Shajimoon A, Afroz R, Gabr M, Thomas W, Little P, et al.
FEBS J
. 2021 Nov;
289(9):2642-2656.
PMID: 34826189
Transforming growth factor (TGF)-β signalling commences with the engagement of TGF-β ligand to cell surface TGF-β receptors (TGFBR) stimulating Smad2 carboxyl-terminal phosphorylation (phospho-Smad2C) and downstream biological responses. In several cell...
6.
Sinclair J, Bloxham C, Chiu H, Chew K, Russell J, Yoshikawa Y, et al.
Front Cell Infect Microbiol
. 2021 Oct;
11:714440.
PMID: 34595130
People with diabetes mellitus are susceptible to both cardiovascular disease and severe influenza A virus infection. We hypothesized that diabetes also increases risks of influenza-associated cardiac complications. A murine type...
7.
OBrien S, Johnstone E, Devost D, Conroy J, Reichelt M, Purdue B, et al.
Biochem Pharmacol
. 2021 Sep;
192:114756.
PMID: 34509100
No abstract available.
8.
Redd M, Scheuer S, Saez N, Yoshikawa Y, Chiu H, Gao L, et al.
Circulation
. 2021 Jul;
144(12):947-960.
PMID: 34264749
Background: Ischemia-reperfusion injury (IRI) is one of the major risk factors implicated in morbidity and mortality associated with cardiovascular disease. During cardiac ischemia, the buildup of acidic metabolites results in...
9.
Wang Z, Chan H, Gambarotta G, Smith N, Purdue B, Pennisi D, et al.
J Cell Physiol
. 2021 Jun;
236(12):8160-8170.
PMID: 34170016
Epidermal growth factor (EGF) receptors (ErbB1-ErbB4) promote cardiac development and growth, although the specific EGF ligands and receptor isoforms involved in growth/repair versus pathology remain undefined. We challenged ventricular cardiomyocytes...
10.
Johnstone E, Abhayawardana R, See H, Seeber R, OBrien S, Thomas W, et al.
Biochem Pharmacol
. 2021 Mar;
188:114521.
PMID: 33741329
Transactivation of the epidermal growth factor receptor (EGFR) by the angiotensin II (AngII) type 1 (AT) receptor is involved in AT receptor-dependent growth effects and cardiovascular pathologies, however the mechanisms...