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Wai Tat Wong

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Articles 22
Citations 171
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Recent Articles
1.
Roberts J, Sime F, Lipman J, Hernandez-Mitre M, Baptista J, Bruggemann R, et al.
Intensive Care Med . 2025 Feb; 51(2):302-317. PMID: 39899034
Purpose: Appropriate antifungal therapy is a major determinant of survival in critically ill patients with invasive fungal disease. We sought to describe whether contemporary dosing of antifungals achieves therapeutic exposures...
2.
Kumta N, Heffernan A, Cotta M, Liu X, Parker S, Wallis S, et al.
Antimicrob Agents Chemother . 2024 Dec; 69(2):e0060124. PMID: 39699210
Ventriculitis in neurocritical care patients leads to significant morbidity and mortality. Antibiotic dose optimization targeting pharmacokinetic/pharmacodynamic (PK/PD) exposures associated with improved bacterial killing may improve therapeutic outcomes. We sought to...
3.
Chen H, Liu W, Coker O, Qin N, Chen H, Wang Y, et al.
Heliyon . 2024 May; 10(8):e29572. PMID: 38699748
Sepsis is a life-threatening illness caused by the dysregulated host response to infection. Nevertheless, our current knowledge of the microbial landscape in the blood of septic patients is still limited....
4.
Roberts J, Sime F, Lipman J, Hernandez-Mitre M, Baptista J, Bruggemann R, et al.
Crit Care Resusc . 2023 Oct; 25(1):1-5. PMID: 37876989
Objective: To describe whether contemporary dosing of antifungal drugs achieves therapeutic exposures in critically ill patients that are associated with optimal outcomes. Adequate antifungal therapy is a key determinant of...
5.
Ling L, Zhang J, Chang L, Chiu L, Ho S, Ng P, et al.
Clin Infect Dis . 2023 Aug; 80(1):91-100. PMID: 37596856
Background: Sepsis surveillance using electronic health record (EHR)-based data may provide more accurate epidemiologic estimates than administrative data, but experience with this approach to estimate population-level sepsis burden is lacking....
6.
Chu R, Zhao S, Zhang J, Chan K, Ng P, Chan C, et al.
BMJ Open . 2023 Jul; 13(7):e067101. PMID: 37429680
Objectives: Direct comparisons between COVID-19 and influenza A in the critical care setting are limited. The objective of this study was to compare their outcomes and identify risk factors for...
7.
Joynt G, Ling L, Wong W, Lipman J
Expert Rev Clin Pharmacol . 2023 Mar; 16(8):703-714. PMID: 36942827
Introduction: The importance of antibiotic treatment for sepsis in critically ill septic patients is well established. Consistently achieving the dose of antibiotics required to optimally kill bacteria, minimize the development...
8.
Yuen J, See C, Cheung J, Lum C, Lee J, Wong W
BMC Med Educ . 2023 Jan; 23(1):20. PMID: 36631787
Background: To investigate the impact of a serious illness communication skills training course on medical students' attitudes regarding clinical empathy, self-efficacy in empathic communication, and learning on different dimensions of...
9.
Wang G, Lam W, Ling L, Ma M, Ramakrishnan S, Chan D, et al.
Clin Chem . 2022 Dec; 69(2):189-201. PMID: 36576350
Background: Nuclear-derived cell-free DNA (cfDNA) molecules in blood plasma are nonrandomly fragmented, bearing a wealth of information related to tissues of origin. DNASE1L3 (deoxyribonuclease 1 like 3) is an important...
10.
Cho C, Ko W, Ngan O, Wong W
Int J Environ Res Public Health . 2022 Sep; 19(17). PMID: 36078203
This study aims to understand professionalism dilemmas medical students have experienced during clinical clerkships and the resulting moral distress using an explanatory mixed-method sequential design-an anonymous survey followed by in-depth...