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Wadim M I de Boon

Explore the profile of Wadim M I de Boon including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 49
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Recent Articles
1.
Henriksen K, Broekhuizen K, de Boon W, Karsdal M, Bihlet A, Christiansen C, et al.
Br J Clin Pharmacol . 2021 May; 87(12):4786-4796. PMID: 34019711
There is a need for antidiabetic agents successfully targeting insulin sensitivity and treating obesity control at the same time. The aim of this first-in-human study was (a) to evaluate safety...
2.
van Brummelen E, Ziagkos D, de Boon W, Hart E, Doll R, Huttunen T, et al.
J Clin Mov Disord . 2020 Apr; 7:4. PMID: 32280482
Background: To quantify pharmacological effects on tremor in patients with essential tremor (ET) or Parkinson's Disease (PD), laboratory-grade accelerometers have previously been used. Over the last years, consumer products such...
3.
van Esdonk M, Stevens J, Stuurman F, de Boon W, Dehez M, van der Graaf P, et al.
J Cardiovasc Pharmacol . 2019 Jul; 74(2):128-136. PMID: 31306369
The quantification of the effect of pharmacological treatment on the cardiovascular system is complicated because of the high level of interindividual and circadian variability. Recently, a dopamine-somatostatin chimera, BIM23B065, was...
4.
de Boon W, van Esdonk M, Stuurman F, Biermasz N, Pons L, Paty I, et al.
J Clin Endocrinol Metab . 2018 Oct; 104(3):883-891. PMID: 30371791
Context: A somatostatin-dopamine chimera (BIM23B065) was under investigation to reduce GH secretion for the treatment of pituitary adenomas. Objective: To determine pharmacokinetics, safety, and tolerability and to monitor hormonal changes...
5.
Post I, de Boon W, Heger M, van Wijk A, Kroon J, van Buul J, et al.
Exp Cell Res . 2013 Jun; 319(17):2501-13. PMID: 23792081
Introduction: Endothelial barrier function is pivotal for the outcome of organ transplantation. Since hypothermic preservation (gold standard) is associated with cold-induced endothelial damage, endothelial barrier function may benefit from organ...
6.
Harms F, de Boon W, Balestra G, Bodmer S, Johannes T, Stolker R, et al.
J Biophotonics . 2011 Jul; 4(10):731-9. PMID: 21770036
Mitochondrial oxygen tension can be measured in vivo by means of oxygen-dependent quenching of delayed fluorescence of protoporphyrin IX (PpIX). Here we demonstrate that delayed fluorescence is readily observed from...