Jaap D van Buul
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Explore the profile of Jaap D van Buul including associated specialties, affiliations and a list of published articles.
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116
Citations
3057
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Recent Articles
1.
Houtzager J, Houtzager J, van Stalborch A, van Stalborch A, Hofstee C, Gulik T, et al.
Vasc Biol
. 2025 Jan;
7(1).
PMID: 39812559
Donor liver preservation methods and solutions have evolved over the last years. Liver sinusoidal endothelial cell (LSEC) barrier function and integrity during preservation are crucial for outcomes of liver transplantation....
2.
Bleckwehl T, Babler A, Tebens M, Maryam S, Nyberg M, Bosteen M, et al.
Nat Cardiovasc Res
. 2024 Dec;
4(1):26-44.
PMID: 39715784
Atherosclerosis is a pervasive contributor to ischemic heart disease and stroke. Despite the advance of lipid-lowering therapies and anti-hypertensive agents, the residual risk of an atherosclerotic event remains high, and...
3.
Sajib M, Zahra F, Lamprou M, Akwii R, Park J, Osorio M, et al.
bioRxiv
. 2024 Oct;
PMID: 39372784
The endothelial barrier plays an active role in transendothelial tumor cell migration during metastasis, however, the endothelial regulatory elements of this step remain obscure. Here we show that endothelial RhoA...
4.
Apelin modulates inflammation and leukocyte recruitment in experimental autoimmune encephalomyelitis
Park H, Song J, Jeong H, Gronloh M, Koh B, Bovay E, et al.
Nat Commun
. 2024 Jul;
15(1):6282.
PMID: 39060233
Demyelination due to autoreactive T cells and inflammation in the central nervous system are principal features of multiple sclerosis (MS), a chronic and highly disabling human disease affecting brain and...
5.
Rademakers T, Manca M, Jin H, Orban T, Perisic L, Frissen H, et al.
Angiogenesis
. 2024 May;
27(3):461-474.
PMID: 38780883
The presence of atherosclerotic plaque vessels is a critical factor in plaque destabilization. This may be attributable to the leaky phenotype of these microvessels, although direct proof for this notion...
6.
van den Brink D, Kleinveld D, Bongers A, Vos J, Roelofs J, Weber N, et al.
J Clin Med
. 2023 Oct;
12(20).
PMID: 37892576
Septic shock is characterized by endothelial dysfunction, leading to tissue edema and organ failure. Heparan sulfate (HS) is essential for vascular barrier integrity, possibly via albumin as a carrier. We...
7.
van den Brink D, Kleinveld D, Bongers A, Vos J, Roelofs J, Weber N, et al.
Intensive Care Med Exp
. 2023 Sep;
11(1):62.
PMID: 37728777
Background: Endothelial injury and permeability are a hallmark of sepsis. Initial resuscitation of septic patients with crystalloids is associated with aggravation of endothelial permeability, which may be related either to...
8.
Luk S, Schoppmeyer R, Ijsselsteijn M, Somarakis A, Acem I, Remst D, et al.
Cancer Immunol Res
. 2023 Sep;
11(11):1480-1492.
PMID: 37695550
Cancers evade T-cell immunity by several mechanisms such as secretion of anti-inflammatory cytokines, down regulation of antigen presentation machinery, upregulation of immune checkpoint molecules, and exclusion of T cells from...
9.
Gronloh M, Tebbens M, Kotsi M, Arts J, van Buul J
Vasc Biol
. 2023 Aug;
5(1).
PMID: 37565726
Intercellular adhesion molecules (ICAMs) are cell surface proteins that play a crucial role in the body's immune response and inflammatory processes. ICAM1 and ICAM2 are two ICAM family members expressed...
10.
van der Krogt J, van der Meulen I, van Buul J
Curr Opin Physiol
. 2023 Aug;
34:None.
PMID: 37547802
The vasculature is characterized by a thin cell layer that comprises the inner wall of all blood vessels, the continuous endothelium. Endothelial cells can also be found in the eye's...