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Wade Wang

Explore the profile of Wade Wang including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 264
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Recent Articles
1.
Katsikis G, Hwang I, Wang W, Bhat V, McIntosh N, Karim O, et al.
Nano Lett . 2022 Feb; 22(4):1511-1517. PMID: 35148107
Quantifying the composition of viral vectors used in vaccine development and gene therapy is critical for assessing their functionality. Adeno-associated virus (AAV) vectors, which are the most widely used viral...
2.
Hsu B, Hagerman S, Jamieson K, Castleberry S, Wang W, Holler E, et al.
ACS Biomater Sci Eng . 2021 Jan; 1(3):148-156. PMID: 33429517
Uncontrolled bleeding and infection are the major causes of death and morbidity from traumatic wounds during military conflicts, disasters, and accidents. Because immediate treatment is critical to survival, it is...
3.
He H, Sofman M, Wang A, Ahrens C, Wang W, Griffith L, et al.
Biomacromolecules . 2019 Dec; 21(2):566-580. PMID: 31846304
Expanding the toolkit of modular and functional synthetic material systems for biomimetic extracellular matrices (ECMs) is needed for achieving more predictable and characterizable cell culture. In the present study, we...
4.
Boehnke N, Correa S, Hao L, Wang W, Straehla J, Bhatia S, et al.
Angew Chem Int Ed Engl . 2019 Nov; 59(7):2776-2783. PMID: 31747099
Layer-by-layer nanoparticles (NPs) are modular drug delivery vehicles that incorporate multiple functional materials through sequential deposition of polyelectrolytes onto charged nanoparticle cores. Herein, we combined the multicomponent features and tumor...
5.
Joo W, Wang W, Mesch R, Matsuzawa K, Liu D, Willson C
J Am Chem Soc . 2019 Aug; 141(37):14736-14741. PMID: 31460760
Preparation of an unzipping polyester is reported. The monomer was prepared from benzoic acid in a four-step sequence. Step growth polymerization of the monomer provides the target polymer. Efficient depolymerization...
6.
Boopathy A, Mandal A, Kulp D, Menis S, Bennett N, Watkins H, et al.
Proc Natl Acad Sci U S A . 2019 Jul; 116(33):16473-16478. PMID: 31358641
Sustained exposure of lymphoid tissues to vaccine antigens promotes humoral immunity, but traditional bolus immunizations lead to rapid antigen clearance. We describe a technology to tailor vaccine kinetics in a...
7.
Wu C, Li J, Wang W, Hammond P
ACS Nano . 2018 Jun; 12(7):6504-6514. PMID: 29944833
The delivery of small interfering RNA (siRNA) remains a major hurdle for the clinical translation of RNA interference (RNAi) therapeutics. Because of its low valency and rigid nature, siRNA typically...
8.
Li J, Wu C, Wang W, He Y, Elkayam E, Joshua-Tor L, et al.
Proc Natl Acad Sci U S A . 2018 Feb; 115(12):E2696-E2705. PMID: 29432194
Small interfering RNA (siRNA) represents a promising class of inhibitors in both fundamental research and the clinic. Numerous delivery vehicles have been developed to facilitate siRNA delivery. Nevertheless, achieving highly...
9.
Li J, He Y, Wang W, Wu C, Hong C, Hammond P
Angew Chem Int Ed Engl . 2017 Sep; 56(44):13709-13712. PMID: 28925033
Messenger RNA (mRNA) represents a promising class of nucleic acid drugs. Although numerous carriers have been developed for mRNA delivery, the inefficient mRNA expression inside cells remains a major challenge....
10.
Li J, Wang W, He Y, Li Y, Yan E, Zhang K, et al.
ACS Nano . 2017 Feb; 11(3):2531-2544. PMID: 28157292
Messenger RNA (mRNA) represents a promising class of nucleic-acid-based therapeutics. While numerous nanocarriers have been developed for mRNA delivery, the inherent labile nature of mRNA results in a very low...