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Wa Du

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Articles 18
Citations 578
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Recent Articles
1.
Park C, Bridges C, Lewis A, Chen T, Shai S, Du W, et al.
Exp Hematol . 2025 Feb; 144:104730. PMID: 39900173
The transcription factor Krüppel-like factor 4 (KLF4) acts as a transcriptional activator and repressor. KLF4 plays a role in various cellular processes, including the dedifferentiation of somatic cells into induced...
2.
Wang X, Du W, Li Y, Yang H, Zhang Y, Akbar R, et al.
JCI Insight . 2024 Mar; 9(5). PMID: 38456501
Efficient clearance and degradation of apoptotic cardiomyocytes by macrophages (collectively termed efferocytosis) is critical for inflammation resolution and restoration of cardiac function after myocardial ischemia/reperfusion (I/R). Here, we define secreted...
3.
Zhao H, Wang P, Wang X, Du W, Yang H, Liu Y, et al.
Cardiovasc Res . 2023 Jul; 119(10):1981-1996. PMID: 37392461
Aims: Systemic inflammation occurs commonly during many human disease settings and increases vascular permeability, leading to organ failure, and lethal outcomes. Lipocalin 10 (Lcn10), a poorly characterized member of the...
4.
Ren L, Du W, Song D, Lu H, Hamblin M, Wang C, et al.
iScience . 2023 Jan; 26(1):105769. PMID: 36594018
Multiple genome-wide association studies (GWAS) have identified specific genetic variants in the coiled-coil domain containing 92 () locus that is associated with obesity and type 2 diabetes in humans. However,...
5.
Lewis A, Bridges C, Moorshead D, Chen T, Du W, Zorman B, et al.
Stem Cells . 2022 May; 40(8):736-750. PMID: 35535819
Acute myeloid leukemia (AML) is an aggressive malignancy of the bone marrow with 5-year overall survival of less than 10% in patients over the age of 65. Limited progress has...
6.
Lu H, Du W, Ren L, Hamblin M, Becker R, Chen Y, et al.
J Am Heart Assoc . 2021 Nov; 10(24):e023601. PMID: 34796717
Aortic aneurysm, including thoracic aortic aneurysm and abdominal aortic aneurysm, is the second most prevalent aortic disease following atherosclerosis, representing the ninth-leading cause of death globally. Open surgery and endovascular...
7.
Shi Z, Mori-Akiyama Y, Du W, Fultz R, Zhao Y, Ruan W, et al.
Cell Mol Gastroenterol Hepatol . 2021 Nov; 13(3):717-737. PMID: 34781022
Background & Aims: We previously showed that histamine suppressed inflammation-associated colonic tumorigenesis through histamine type 2 receptor (H2R) signaling in mice. This study aimed to precisely elucidate the downstream effects...
8.
Chen T, Du W, Junco J, Bridges C, Shen Y, Puppi M, et al.
Oncotarget . 2021 Sep; 12(18):1787-1801. PMID: 34504651
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive pediatric leukemia with a worse prognosis than most frequent B-cell ALL due to a high incidence of treatment failures and relapse. Our...
9.
Du W, Ren L, Hamblin M, Fan Y
Biomedicines . 2021 Feb; 9(2). PMID: 33546224
Angiogenesis, a process of new blood vessel formation from the pre-existing vascular bed, is a critical event in various physiological and pathological settings. Over the last few years, the role...
10.
Phung T, Du W, Xue Q, Ayyaswamy S, Gerald D, Antonello Z, et al.
Cancer Res . 2014 Nov; 75(1):40-50. PMID: 25388284
Vascular tumors are endothelial cell neoplasms whose mechanisms of tumorigenesis are poorly understood. Moreover, current therapies, particularly those for malignant lesions, have little beneficial effect on clinical outcomes. In this...