W Zachariae
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Explore the profile of W Zachariae including associated specialties, affiliations and a list of published articles.
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18
Citations
2220
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Recent Articles
1.
Zachariae W, Shevchenko A
Biochem Soc Trans
. 2000 Aug;
27(4):549-54.
PMID: 10917640
No abstract available.
2.
Zachariae W
Curr Opin Cell Biol
. 1999 Dec;
11(6):708-16.
PMID: 10600711
Progression through mitosis is controlled by cyclin-dependent kinases, which drive cells into metaphase, and by the anaphase-promoting complex/cyclosome, a ubiquitin ligase that triggers sister chromatid separation and exit from mitosis....
3.
4.
Epitope tagging of yeast genes using a PCR-based strategy: more tags and improved practical routines
Knop M, Siegers K, Pereira G, Zachariae W, Winsor B, Nasmyth K, et al.
Yeast
. 1999 Jul;
15(10B):963-72.
PMID: 10407276
Epitope tagging of proteins as a strategy for the analysis of function, interactions and the subcellular distribution of proteins has become widely used. In the yeast Saccharomyces cerevisiae, molecular biological...
5.
Seol J, Feldman R, Zachariae W, Correll C, Lyapina S, Chi Y, et al.
Genes Dev
. 1999 Jul;
13(12):1614-26.
PMID: 10385629
SCFCdc4 (Skp1, Cdc53/cullin, F-box protein) defines a family of modular ubiquitin ligases (E3s) that regulate diverse processes including cell cycle, immune response, and development. Mass spectrometric analysis of proteins copurifying...
6.
Alexandru G, Zachariae W, Schleiffer A, Nasmyth K
EMBO J
. 1999 May;
18(10):2707-21.
PMID: 10329618
In yeast, anaphase entry depends on Pds1 proteolysis, while chromosome re-duplication in the subsequent S-phase involves degradation of mitotic cyclins such as Clb2. Sequential proteolysis of Pds1 and mitotic cyclins...
7.
Grossberger R, Gieffers C, Zachariae W, Podtelejnikov A, Schleiffer A, Nasmyth K, et al.
J Biol Chem
. 1999 May;
274(20):14500-7.
PMID: 10318877
The anaphase-promoting complex/cyclosome (APC) is a ubiquitin-protein ligase whose activity is essential for progression through mitosis. The vertebrate APC is thought to be composed of 8 subunits, whereas in budding...
8.
Zachariae W, Schwab M, Nasmyth K, Seufert W
Science
. 1998 Nov;
282(5394):1721-4.
PMID: 9831566
Proteolysis of mitotic cyclins depends on a multisubunit ubiquitin-protein ligase, the anaphase promoting complex (APC). Proteolysis commences during anaphase, persisting throughout G1 until it is terminated by cyclin-dependent kinases (CDKs)...
9.
Ciosk R, Zachariae W, Michaelis C, Shevchenko A, Mann M, Nasmyth K
Cell
. 1998 Jul;
93(6):1067-76.
PMID: 9635435
Cohesion between sister chromatids during G2 and M phases depends on the "cohesin" protein Scc1p (Mcd1p). Loss of cohesion at the metaphase to anaphase transition is accompanied by Scc1p's dissociation...
10.
Shirayama M, Zachariae W, Ciosk R, Nasmyth K
EMBO J
. 1998 Apr;
17(5):1336-49.
PMID: 9482731
Proteolysis mediated by the anaphase promoting complex (APC) has a crucial role in regulating the passage of cells through anaphase. Destruction of the anaphase inhibitor Pds1p is necessary for separation...