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W Thomas Johnson

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Articles 25
Citations 383
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Recent Articles
1.
Xie L, Zhang K, Rasmussen D, Wang J, Wu D, Roemmich J, et al.
PLoS One . 2017 Feb; 12(1):e0169581. PMID: 28141871
Adipose tissue macrophages (ATM) are implicated in adipose tissue inflammation and obesity-related insulin resistance. Maternal low protein models result in fetal programming of obesity. The study aims to answer whether...
2.
Claycombe K, Roemmich J, Johnson L, Vomhof-DeKrey E, Johnson W
J Nutr Biochem . 2014 Dec; 26(2):184-9. PMID: 25483313
Malnutrition during the fetal growth period increases risk for later obesity and type 2 diabetes mellitus (T2DM). We have shown that a prenatal low-protein (8% protein; LP) diet followed by...
3.
Johnson W, Nordlie R, Levay L
Biol Trace Elem Res . 2013 Nov; 6(5):369-78. PMID: 24264174
Copper deficiency has been reported to cause glucose intolerance in rats by interfering with normal glucose utilization. Accordingly, copper deficiency was produced in rats to study its effects on glucose-6-P...
4.
Claycombe K, Uthus E, Roemmich J, Johnson L, Johnson W
J Nutr . 2013 Aug; 143(10):1533-9. PMID: 23946348
Maternal low-protein diets result in lower birth weight followed by accelerated catch-up growth that is accompanied by the development of obesity and glucose intolerance in later life. Whether postnatal high-fat...
5.
Johnson W, Newman Jr S
J Am Aging Assoc . 2013 Apr; 26(1-2):19-28. PMID: 23604915
Heart mitochondria experience age-related declines in cytochrome c oxidase (CCO) activity and increases in the generation of reactive oxygen species (ROS) that may contribute to loss of cardiac function and...
6.
Song M, Schuschke D, Zhou Z, Chen T, Shi X, Zhang J, et al.
Obesity (Silver Spring) . 2013 Mar; 21(8):1669-75. PMID: 23512597
Objective: Dietary fructose and copper interaction may play an important role in the pathogenesis of nonalcoholic fatty liver disease. In this study, whether or not modest fructose consumption (3% fructose,...
7.
Wakeham K, Webb E, Sebina I, Muhangi L, Miley W, Johnson W, et al.
Infect Agent Cancer . 2011 Oct; 6(1):15. PMID: 21962023
Background: Immune modulation by parasites may influence susceptibility to bacteria and viruses. We examined the association between current parasite infections, HIV and syphilis (measured in blood or stool samples using...
8.
Song M, Schuschke D, Zhou Z, Chen T, Pierce Jr W, Wang R, et al.
J Hepatol . 2011 Jul; 56(2):433-40. PMID: 21781943
Background & Aims: Dietary copper deficiency is associated with a variety of manifestations of the metabolic syndrome, including hyperlipidemia and fatty liver. Fructose feeding has been reported to exacerbate complications...
9.
Brown-Borg H, Johnson W, Rakoczy S
Age (Dordr) . 2011 Feb; 34(1):43-57. PMID: 21327718
Reduced signaling of the growth hormone (GH)/insulin-like growth factor-1 (IGF-1) pathway is associated with extended life span in several species. Ames dwarf mice are GH-deficient and live >50% longer than...
10.
Schuschke D, Adeagbo A, Patibandla P, Egbuhuzo U, Fernandez-Botran R, Johnson W
Inflammation . 2009 Jul; 32(5):333-9. PMID: 19609832
Copper deficiency inactivates Cu/Zn-SOD and promotes accumulation of reactive oxygen species. This process likely impairs nitric oxide (NO)-mediated relaxation as well as triggers vascular inflammation. The current study was designed...