W P Meehan
Overview
Explore the profile of W P Meehan including associated specialties, affiliations and a list of published articles.
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30
Citations
608
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Recent Articles
1.
Goetze S, Kintscher U, Kim S, Meehan W, Kaneshiro K, Collins A, et al.
J Cardiovasc Pharmacol
. 2001 Nov;
38(6):909-21.
PMID: 11707695
Vascular smooth muscle cell (VSMC) migration involves adhesion, locomotion, and invasion regulated by various signaling molecules, among which the extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinases (MAPK) play a critical role....
2.
Goetze S, Kintscher U, Kaneshiro K, Meehan W, Collins A, Fleck E, et al.
Atherosclerosis
. 2001 Nov;
159(1):93-101.
PMID: 11689211
Migration, proliferation and differentiation of vascular smooth muscle cells (VSMC) and macrophages are important pathological responses that contribute to the development and progression of vascular lesions. Cytokines such as TNFalpha...
3.
Collins A, Meehan W, Kintscher U, Jackson S, Wakino S, Noh G, et al.
Arterioscler Thromb Vasc Biol
. 2001 Mar;
21(3):365-71.
PMID: 11231915
Peroxisome proliferator-activated receptor-gamma (PPARgamma) is a ligand-activated nuclear receptor expressed in all of the major cell types found in atherosclerotic lesions: monocytes/macrophages, endothelial cells, and smooth muscle cells. In vitro,...
4.
Kappert K, Blaschke F, Meehan W, Kawano H, Grill M, Fleck E, et al.
Basic Res Cardiol
. 2001 Feb;
96(1):42-9.
PMID: 11215531
Neointima formation involves tissue expression of matrix proteins and growth factors. The role of alphavbeta3, but not alphavbeta5 integrin in vascular cells has been sufficiently investigated. The aim of the...
5.
Goetze S, Kim S, Xi X, Graf K, Yang D, Fleck E, et al.
J Cardiovasc Pharmacol
. 2000 May;
35(5):749-57.
PMID: 10813377
Troglitazone (TRO) is an oral insulin-sensitizer that has direct effects on the vasculature to inhibit cell growth and migration. In vascular smooth muscle cells (VSMCs), insulin transduces a mitogenic signal...
6.
Law R, Goetze S, Xi X, Jackson S, Kawano Y, Demer L, et al.
Circulation
. 2000 Mar;
101(11):1311-8.
PMID: 10725292
Background: Peroxisome proliferator-activated receptor-gamma (PPARgamma) is activated by fatty acids, eicosanoids, and insulin-sensitizing thiazolidinediones (TZDs). The TZD troglitazone (TRO) inhibits vascular smooth muscle cell (VSMC) proliferation and migration in vitro...
7.
Shih J, Ridd M, Chen K, Meehan W, Kung M, Seif I, et al.
Brain Res
. 1999 Jul;
835(2):104-12.
PMID: 10415365
Mice deficient in monoamine oxidase A (MAO A) have elevated brain levels of 5-HT and manifest enhanced aggression. We used these mice as a model to study the role of...
8.
Schwarz E, Pollick C, Meehan W, Kloner R
Basic Res Cardiol
. 1999 Jan;
93(6):477-86.
PMID: 9879454
Objectives: The efficacy of three different echocardiographic techniques to assess cardiac structures and function in the rat heart was studied. Background: With increasing costs for large animal studies there is...
9.
Graf K, Do Y, Ashizawa N, Meehan W, Giachelli C, Marboe C, et al.
Circulation
. 1997 Dec;
96(9):3063-71.
PMID: 9386176
Background: Osteopontin (OP) has been identified in cultured rat cardiac fibroblasts, where it contributes to angiotensin II (AII)-induced remodeling processes; in cultured cardiomyocytes; and in macrophages in cardiac tissues with...
10.
Meehan J, Meehan W
Acta Physiol Scand Suppl
. 1997 Jan;
640:26-9.
PMID: 9401600
James Paget Henry really began his productive research career at the outset of the second world war. His studies of acceleration and the anoxia of high altitude were supported by...