W L Stanford
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Explore the profile of W L Stanford including associated specialties, affiliations and a list of published articles.
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16
Citations
1284
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Recent Articles
1.
Pi L, Rooprai J, Allan D, Atkins H, Bredeson C, Fulcher A, et al.
Leuk Res
. 2019 Sep;
86:106222.
PMID: 31522038
Introduction: Mouse double minute 2 protein (MDM2), a negative regulator of the p53 tumour suppressor gene, is frequently amplified in malignancies. MDM2 antagonists have shown efficacy in treating malignancies with...
2.
Lee W, Hurtig M, Pilliar R, Stanford W, Kandel R
Osteoarthritis Cartilage
. 2015 Apr;
23(8):1307-15.
PMID: 25891750
Objective: In healthy joints, a zone of calcified cartilage (ZCC) provides the mechanical integration between articular cartilage and subchondral bone. Recapitulation of this architectural feature should serve to resist the...
3.
Chitilian J, Thillainadesan G, Manias J, Chang W, Walker E, Isovic M, et al.
Stem Cells
. 2013 Oct;
32(1):204-15.
PMID: 24115386
p/CIP, also known as steroid receptor coactivator 3 (SRC-3)/Nuclear Receptor Coactivator 3 (NCoA3), is a transcriptional coactivator that binds liganded nuclear hormone receptors, as well as other transcription factors, and...
4.
Stanford W, COHN J, Cordes S
Nat Rev Genet
. 2001 Oct;
2(10):756-68.
PMID: 11584292
Although at least 35,000 human genes have been sequenced and mapped, adequate expression or functional information is available for only approximately 15% of them. Gene-trap mutagenesis is a technique that...
5.
Joza N, Susin S, Daugas E, Stanford W, Cho S, Li C, et al.
Nature
. 2001 Mar;
410(6828):549-54.
PMID: 11279485
Programmed cell death is a fundamental requirement for embryogenesis, organ metamorphosis and tissue homeostasis. In mammals, release of mitochondrial cytochrome c leads to the cytosolic assembly of the apoptosome-a caspase...
6.
Sasaki T, Irie-Sasaki J, Jones R, Stanford W, Bolon B, Wakeham A, et al.
Science
. 2000 Feb;
287(5455):1040-6.
PMID: 10669416
Phosphoinositide 3-kinases (PI3Ks) regulate fundamental cellular responses such as proliferation, apoptosis, cell motility, and adhesion. Viable gene-targeted mice lacking the p110 catalytic subunit of PI3Kgamma were generated. We show that...
7.
Hidaka M, Caruana G, Stanford W, Sam M, Correll P, Bernstein A
Mech Dev
. 1999 Dec;
90(1):3-15.
PMID: 10585558
Using an expression gene trapping strategy, we have identified and characterized two novel hematopoietic genes, Hzf and Hhl. Embryonic stem (ES) cells containing a gene trap vector insertion were cultured...
8.
Hidaka M, Stanford W, Bernstein A
Proc Natl Acad Sci U S A
. 1999 Jun;
96(13):7370-5.
PMID: 10377421
Genetic studies in mice have previously demonstrated an intrinsic requirement for the vascular endothelial growth factor (VEGF) receptor Flk-1 in the early development of both the hematopoietic and endothelial cell...
9.
Stanford W, Caruana G, Vallis K, Inamdar M, Hidaka M, Bautch V, et al.
Blood
. 1998 Dec;
92(12):4622-31.
PMID: 9845528
We have developed a large-scale, expression-based gene trap strategy to perform genome-wide functional analysis of the murine hematopoietic and vascular systems. Using two different gene trap vectors, we have isolated...
10.
Stanford W, Haque S, Alexander R, Liu X, Latour A, Snodgrass H, et al.
J Exp Med
. 1997 Aug;
186(5):705-17.
PMID: 9271586
Ly-6A is a murine antigen which is implicated in lymphocyte activation and may be involved in activation of hematopoietic stem cells. Antibody cross-linking studies and antisense experiments have suggested that...