W James Gauderman
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Explore the profile of W James Gauderman including associated specialties, affiliations and a list of published articles.
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7802
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Recent Articles
1.
Lee S, Miller C, Bentley A, Brown M, Nagarajan P, Noordam R, et al.
Res Sq
. 2025 Mar;
PMID: 40034430
Background Gene-environment interactions may enhance our understanding of hypertension. Our previous study highlighted the importance of considering psychosocial factors in gene discovery for blood pressure (BP) but was limited in...
2.
Po J, Morrison J, Marian B, Chen Z, Gauderman W, Garcia E
Genet Epidemiol
. 2025 Jan;
49(1):e70000.
PMID: 39865338
Gene-environment interactions have been observed for childhood asthma, however few have been assessed in ethnically diverse populations. Thus, we examined how polygenic risk score (PRS) modifies the association between ambient...
3.
Gauderman W, Fu Y, Queme B, Kawaguchi E, Wang Y, Morrison J, et al.
bioRxiv
. 2025 Jan;
PMID: 39763728
A polygenic risk score (PRS) is used to quantify the combined disease risk of many genetic variants. For complex human traits there is interest in determining whether the PRS modifies,...
4.
Wang X, Zhong C, Ma X, Metayer C, Mancuso N, Gauderman W, et al.
Cancer Epidemiol Biomarkers Prev
. 2024 Nov;
34(1):100-107.
PMID: 39495115
Background: Acute lymphoblastic leukemia (ALL) is the most common type of cancer among children. Tobacco exposure during gestation has been investigated as a potential risk factor, but its role remains...
5.
Guo F, Habre R, Xu Y, Chen X, Howland S, Lurmann F, et al.
Environ Res
. 2024 Oct;
263(Pt 2):120130.
PMID: 39419260
Background: Little is known about how childhood exposure to traffic-related air pollution (TRAP) and stress interact to affect adults' cardiometabolic health. We examined this interaction and assessed the impact of...
6.
Thomas C, Lin Y, Kim M, Kawaguchi E, Qu C, Um C, et al.
Epidemiology
. 2024 Sep;
36(1):126-138.
PMID: 39316822
Background: Colorectal cancer (CRC) is a common, fatal cancer. Identifying subgroups who may benefit more from intervention is of critical public health importance. Previous studies have assessed multiplicative interaction between...
7.
Noordam R, Wang W, Nagarajan P, Wang H, Brown M, Bentley A, et al.
medRxiv
. 2024 Sep;
PMID: 39281768
We performed large-scale genome-wide gene-sleep interaction analyses of lipid levels to identify novel genetic variants underpinning the biomolecular pathways of sleep-associated lipid disturbances and to suggest possible druggable targets. We...
8.
Xiao C, Scales J, Chavda J, Dove R, Tsocheva I, Wood H, et al.
Int J Behav Nutr Phys Act
. 2024 Sep;
21(1):89.
PMID: 39232801
Background: The Ultra-Low Emission Zone (ULEZ), introduced in Central London in April 2019, aims to enhance air quality and improve public health. The Children's Health in London and Luton (CHILL)...
9.
Young W, van der Most P, Bartz T, Bos M, Biino G, Duong T, et al.
J Am Heart Assoc
. 2024 Aug;
13(17):e034760.
PMID: 39206732
Background: Ventricular repolarization time (ECG QT and JT intervals) is associated with malignant arrhythmia. Genome-wide association studies have identified 230 independent loci for QT and JT; however, 50% of their...
10.
Guo F, Chen X, Niu Z, Karim R, Gauderman W, McConnell R, et al.
J Am Heart Assoc
. 2024 Aug;
13(15):e034821.
PMID: 39101497
Background: Echogenicity of the carotid arterial wall, measured by gray scale median of the intima-media complex (IM-GSM), is a novel subclinical atherosclerosis marker with lower values indicating greater lipid deposition....