Juan Pablo Lewinger
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Explore the profile of Juan Pablo Lewinger including associated specialties, affiliations and a list of published articles.
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72
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1197
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Recent Articles
1.
Gauderman W, Fu Y, Queme B, Kawaguchi E, Wang Y, Morrison J, et al.
bioRxiv
. 2025 Jan;
PMID: 39763728
A polygenic risk score (PRS) is used to quantify the combined disease risk of many genetic variants. For complex human traits there is interest in determining whether the PRS modifies,...
2.
Shen D, Lewinger J, Kawaguchi E
BioData Min
. 2024 Oct;
17(1):44.
PMID: 39449073
Background: Associated with high-dimensional omics data there are often "meta-features" such as biological pathways and functional annotations, summary statistics from similar studies that can be informative for predicting an outcome...
3.
Thomas C, Lin Y, Kim M, Kawaguchi E, Qu C, Um C, et al.
Epidemiology
. 2024 Sep;
36(1):126-138.
PMID: 39316822
Background: Colorectal cancer (CRC) is a common, fatal cancer. Identifying subgroups who may benefit more from intervention is of critical public health importance. Previous studies have assessed multiplicative interaction between...
4.
Drew D, Kim A, Lin Y, Qu C, Morrison J, Lewinger J, et al.
Sci Adv
. 2024 May;
10(22):eadk3121.
PMID: 38809988
Regular, long-term aspirin use may act synergistically with genetic variants, particularly those in mechanistically relevant pathways, to confer a protective effect on colorectal cancer (CRC) risk. We leveraged pooled data...
5.
Papadimitriou N, Kim A, Kawaguchi E, Morrison J, Diez-Obrero V, Albanes D, et al.
EBioMedicine
. 2024 May;
104:105146.
PMID: 38749303
Background: Consumption of fibre, fruits and vegetables have been linked with lower colorectal cancer (CRC) risk. A genome-wide gene-environment (G × E) analysis was performed to test whether genetic variants...
6.
Shen D, Lewinger J, Kawaguchi E
bioRxiv
. 2024 Apr;
PMID: 38617211
Background: Associated with high-dimensional omics data there are often "meta-features" such as biological pathways and functional annotations, summary statistics from similar studies that can be informative for predicting an outcome...
7.
Tian Y, Lin Y, Qu C, Arndt V, Baurley J, Berndt S, et al.
Br J Cancer
. 2024 Apr;
130(10):1687-1696.
PMID: 38561434
Background: Menopausal hormone therapy (MHT), a common treatment to relieve symptoms of menopause, is associated with a lower risk of colorectal cancer (CRC). To inform CRC risk prediction and MHT...
8.
Stern M, Sanchez Mendez J, Kim A, Obon-Santacana M, Moratalla-Navarro F, Martin V, et al.
Cancer Epidemiol Biomarkers Prev
. 2023 Dec;
33(3):400-410.
PMID: 38112776
Background: High red meat and/or processed meat consumption are established colorectal cancer risk factors. We conducted a genome-wide gene-environment (GxE) interaction analysis to identify genetic variants that may modify these...
9.
Buckley D, Lewinger J, Gooden G, Spillman M, Neuman M, Guo X, et al.
Clin Cancer Res
. 2023 Oct;
29(24):5196-5206.
PMID: 37812492
Purpose: High-grade serous ovarian carcinoma (HGSOC) is the most lethal epithelial ovarian cancer (EOC) and is often diagnosed at late stage. In women with a known pelvic mass, surgery followed...
10.
Cho A, Lewinger J, Pardeshi A, Apolo Aroca G, Torres M, Nongpiur M, et al.
Transl Vis Sci Technol
. 2023 Sep;
12(9):4.
PMID: 37672252
Purpose: The purpose of this study was to investigate the classification of angle closure eyes based on hierarchical cluster analysis of ocular biometrics measured in the dark and light using...