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W J Esselman

Explore the profile of W J Esselman including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 166
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Recent Articles
1.
Lee K, Esselman W
Cell Signal . 2001 Aug; 13(9):645-52. PMID: 11495722
In Jurkat T lymphocytes, hydrogen peroxide (H(2)O(2)) potentiates the phosphorylation level of extracellular signal-regulated kinase 1 and 2 (ERK1/2) caused by T cell receptor (TCR) stimulation with anti-CD3 and anti-CD28...
2.
Wang Y, Liang L, Esselman W
J Immunol . 2000 Feb; 164(5):2557-64. PMID: 10679094
CD45 contains tandem repeated protein tyrosine phosphatase (PTP) domains and is essential for the initiation of the earliest activation events resulting from Ag ligation of the TCR. The second PTP...
3.
Wang Y, Guo W, Liang L, Esselman W
J Biol Chem . 1999 Mar; 274(11):7454-61. PMID: 10066810
CD45 is a receptor-type protein-tyrosine phosphatase (PTP) that is required for antigen-specific stimulation and proliferation in lymphocytes. This study was designed to determine the nature of specific kinases in lymphocytes...
4.
Kang S, Liao P, Gage D, Esselman W
J Biol Chem . 1997 Apr; 272(17):11588-96. PMID: 9111075
Phosphorylation of CD45, a transmembrane protein-tyrosine phosphatase (PTPase), has been proposed to mediate docking of signaling proteins and to modulate PTPase activity. To study the role of phosphorylation in CD45,...
5.
Zhai Y, Wirth J, WELSCH C, Esselman W
Cancer Treat Res . 1996 Jan; 83:107-25. PMID: 8826644
No abstract available.
6.
Zhai Y, Wirth J, Kang S, WELSCH C, Esselman W
Mol Carcinog . 1995 Oct; 14(2):103-10. PMID: 7576097
The incidence of amplification of neu oncogene-encoded protein tyrosine kinase in human breast cancer strongly supports the concept that protein tyrosine phosphorylation and dephosphorylation are key regulatory mechanisms in the...
7.
Waldmann M, Gunter A, Zaroukian M, Esselman W
J Immunol . 1994 Sep; 153(5):2004-13. PMID: 8051405
CD45 is an abundant cell-surface protein tyrosine phosphatase (PTPase) of hematopoietic cells that mediates specific tyrosine dephosphorylation in lymphocyte Ag activation. The hypothesis that CD45 PTPase activity varies during progression...
8.
Zhai Y, Beittenmiller H, Wang B, Gould M, Oakley C, Esselman W, et al.
Cancer Res . 1993 May; 53(10 Suppl):2272-8. PMID: 8097963
Protein tyrosine phosphorylation/dephosphorylation is a fundamental mechanism in the regulation of cell proliferation and neoplastic transformation; this metabolic process is modulated by the opposing activities of protein tyrosine kinases and...
9.
Zhai Y, Esselman W, Oakley C, Chang C, WELSCH C
Cancer Immunol Immunother . 1992 Jan; 35(4):237-45. PMID: 1511458
The severe combined immunodeficient (SCID) mouse, lacking functional T and B lymphocytes, has been considered by many groups to be a prime candidate for the reconstitution of a human immune...
10.
Bretz J, Chen S, Redenius D, Chang H, Esselman W, Schwartz R
Dev Immunol . 1992 Jan; 2(4):249-61. PMID: 1343095
Recent reports of "lineage switching" from a lymphoid to macrophage phenotype have left unresolved the question of whether such cells are functional macrophages or nonfunctional products of differentiation gone awry....