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W G Coleman Jr

Explore the profile of W G Coleman Jr including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 15
Citations 247
Followers 0
Related Specialties
Microbiology
Biochemistry
General Medicine
Top 10 Co-Authors
L Leive
L Ding
B Seto
S E Ealick
Y Ni
A M Deacon
H E Umbarger
Y S Ni
P McPhie
J C PEGUES
Published In
J Bacteriol
J Biol Chem
Lancet
Acta Crystallogr D Biol Crystallogr
Tokai J Exp Clin Med
Affiliations
Soon will be listed here.
Recent Articles
1.
Evidence that NADP+ is the physiological cofactor of ADP-L-glycero-D-mannoheptose 6-epimerase
Ni Y, McPhie P, Deacon A, Ealick S, Coleman Jr W
J Biol Chem . 2001 Apr; 276(29):27329-34. PMID: 11313358
ADP-L-glycero-D-mannoheptose 6-epimerase is required for lipopolysaccharide inner core biosynthesis in several genera of Gram-negative bacteria. The enzyme contains both fingerprint sequences Gly-X-Gly-X-X-Gly and Gly-X-X-Gly-X-X-Gly near its N terminus, which is...
2.
The crystal structure of ADP-L-glycero-D-mannoheptose 6-epimerase: catalysis with a twist
Deacon A, Ni Y, Coleman Jr W, Ealick S
Structure . 2000 Jul; 8(5):453-62. PMID: 10896473
Background: ADP-L-glycero--mannoheptose 6-epimerase (AGME) is required for lipopolysaccharide (LPS) biosynthesis in most genera of pathogenic and non-pathogenic Gram-negative bacteria. It catalyzes the interconversion of ADP-D-glycero-D-mannoheptose and ADP-L-glycero-D-mannoheptose, a precursor of...
3.
Crystallization and preliminary X-ray diffraction studies of the lipopolysaccharide core biosynthetic enzyme ADP-L-glycero-D-mannoheptose 6-epimerase from Escherichia coli K-12
Ding L, Zhang Y, Deacon A, Ealick S, Ni Y, Sun P, et al.
Acta Crystallogr D Biol Crystallogr . 1999 Mar; 55(Pt 3):685-8. PMID: 10089470
ADP-L-glycero-D-mannoheptose 6-epimerase is a 240 kDa NAD-dependent nucleotide diphosphosugar epimerase from Escherichia coli K12 which catalyzes the interconversion of ADP-D-glycero-D-mannoheptose and ADP-L-glycero-D-mannoheptose. ADP-L-glycero-D-mannoheptose is a required intermediate for lipopolysaccharide inner-core...
4.
Purification and properties of the Escherichia coli K-12 NAD-dependent nucleotide diphosphosugar epimerase, ADP-L-glycero-D-mannoheptose 6-epimerase
Ding L, Seto B, Ahmed S, Coleman Jr W
J Biol Chem . 1994 Sep; 269(39):24384-90. PMID: 7929099
The Escherichia coli K-12 NAD-dependent nucleotide-diphosphosugar epimerase, ADP-L-glycero-D-mannoheptose 6-epimerase, catalyzes the conversion of ADP-D-glycero-D-mannoheptose to ADP-L-glycero-D-mannoheptose. ADP-L-glycero-D-mannoheptose is a key intermediate of lipopolysaccharide inner core biosynthesis in several genera of...
5.
Cloning and characterization of the Escherichia coli K-12 rfa-2 (rfaC) gene, a gene required for lipopolysaccharide inner core synthesis
Chen L, Coleman Jr W
J Bacteriol . 1993 May; 175(9):2534-40. PMID: 8478319
A genetically defined mutation, designated rfa-2, results in altered lipopolysaccharide (LPS) biosynthesis. rfa-2 mutants produce a core-defective LPS that contains lipid A and a single sugar moiety, 2-keto-3-deoxyoctulosonic acid, in...
6.
Cloning, expression, and characterization of the Escherichia coli K-12 rfaD gene
PEGUES J, Chen L, Gordon A, Ding L, Coleman Jr W
J Bacteriol . 1990 Aug; 172(8):4652-60. PMID: 2198271
The rfaD gene encodes ADP-L-glycero-D-mannoheptose-6-epimerase, an enzyme required for the biosynthesis of the lipopolysaccharide precursor ADP-L-glycerol-D-mannoheptose. The precise localization of the rfaD gene on a 1.3-kilobase SspI-HpaI fragment is reported....
7.
Morphology and immunohistochemistry of experimental and human non-A, non-B hepatitis
Schaff Z, Seto B, Coleman Jr W, Lapis K
Tokai J Exp Clin Med . 1986 Jan; 11 Suppl:111-20. PMID: 2454517
The diagnosis of non-A, non-B hepatitis (NANBH) presently depends on the exclusion of hepatitis A, B and other causes of hepatitis, because no specific tests are available for diagnosis. Different...
8.
New cysE-pyrE-linked rfa mutation in Escherichia coli K-12 that results in a heptoseless lipopolysaccharide
Coleman Jr W, Deshpande K
J Bacteriol . 1985 Mar; 161(3):1209-14. PMID: 3882666
A new novobiocin-supersensitive mutant of Escherichia coli K-12 has been characterized biochemically and genetically. Lipopolysaccharide prepared from this mutant strain is truncated and contains 2-keto-3-deoxyoctulosonic acid as its only core...
9.
Detection of reverse transcriptase activity in association with the non-A, non-B hepatitis agent(s)
Seto B, Coleman Jr W, Iwarson S, Gerety R
Lancet . 1984 Oct; 2(8409):941-3. PMID: 6208445
Particle-associated reverse transcriptase activity was detected in four human serum specimens and in two plasma-derived products, all of which had been shown to transmit non-A, non-B hepatitis (NANBH) to other...
10.
Tetracyclines of various hydrophobicities as a probe for permeability of Escherichia coli outer membranes
Leive L, Telesetsky S, Coleman Jr W, Carr D
Antimicrob Agents Chemother . 1984 May; 25(5):539-44. PMID: 6375560
The outer membrane of gram-negative cells excludes hydrophobic molecules and is responsible for the resistance of these cells to a number of dyes, detergents, and antibiotics. We describe a test...